Increased camptothecin toxicity induced in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I (Q74393005)

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10 November 2019

title

Increased camptothecin toxicity induced in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I (English)

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10 November 2019

main subject

Saccharomyces cerevisiae

1 reference

C Hann

1

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10 November 2019

D L Evans

2

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10 November 2019

J Fertala

3

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10 November 2019

P Benedetti

4

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10 November 2019

M A Bjornsti

5

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10 November 2019

D J Hall

6

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10 November 2019

language of work or name

English

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publication date

1 April 1998

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Journal of Biological Chemistry

10 November 2019

published in

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10 November 2019

volume

273

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10 November 2019

issue

14

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10 November 2019

page(s)

8425-8433

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Topoisomerase Poisons: Harnessing the Dark Side of Enzyme Mechanism

10 November 2019

cites work

1 reference

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21 January 2018

1 reference

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Yeast Saccharomyces cerevisiae as a model system to study the cytotoxic activity of the antitumor drug camptothecin

21 January 2018

1 reference

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DNA topoisomerases: essential enzymes and lethal targets

21 January 2018

1 reference

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Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.14.8425

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

21 January 2018

1 reference

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Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.14.8425

A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons

21 January 2018

1 reference

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DNA topoisomerase I is involved in both repression and activation of transcription

21 January 2018

1 reference

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Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

21 January 2018

1 reference

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Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription

21 January 2018

1 reference

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Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.

21 January 2018

1 reference

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The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs

21 January 2018

1 reference

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Altered shape and cell cycle characteristics of fibroblasts expressing the E2F1 transcription factor

21 January 2018

1 reference

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Different patterns of apoptosis of HL-60 cells induced by cycloheximide and camptothecin

21 January 2018

1 reference

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Major DNA fragmentation is a late event in apoptosis

21 January 2018

1 reference

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Cell cycle analysis of amount and distribution of nuclear DNA topoisomerase I as determined by fluorescence digital imaging microscopy

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.14.8425

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9525954%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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