Construction of a model of the Candida albicans lanosterol 14-alpha-demethylase active site using the homology modelling technique (Q74438445)

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10 November 2019

title

Construction of a model of the Candida albicans lanosterol 14-alpha-demethylase active site using the homology modelling technique (English)

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10 November 2019

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2

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10 November 2019

author name string

H D Höltje

series ordinal

1

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10 November 2019

publication date

1 January 1998

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Pharmaceutica acta Helvetiae

10 November 2019

published in

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10 November 2019

volume

72

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10 November 2019

issue

5

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10 November 2019

page(s)

271-277

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The 3-hydroxy group of lanosterol is essential for orienting the substrate site of cytochrome P-450(14DM) (lanosterol 14 alpha- demethylase)

10 November 2019

cites work

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Structural analysis of the interaction between the side-chain of substrates and the active site of lanosterol 14 alpha-demethylase (P-450(14)DM) of yeast

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Modeling cytochrome P450 14 alpha demethylase (Candida albicans) from P450cam.

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Structure of cytochrome P450eryF involved in erythromycin biosynthesis

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Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase-trimethoprim, a drug-receptor system.

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Crystal structure and refinement of cytochrome P450terp at 2.3 A resolution

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Structure and function of cytochromes P450: a comparative analysis of three crystal structures.

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Purification and properties of cytochrome P-450-dependent 14 alpha-sterol demethylase from Candida albicans

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7 January 2021

Nucleotide sequence of cytochrome P450 L1A1 (lanosterol 14 alpha-demethylase) from Candida albicans

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7 January 2021

The catalytic mechanism of cytochrome P450 BM3 involves a 6 Å movement of the bound substrate on reduction

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Secondary structure prediction of 52 membrane-bound cytochromes P450 shows a strong structural similarity to P450cam

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Crystal structure of substrate-free Pseudomonas putida cytochrome P-450

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Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

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7 January 2021

Molecular modeling of the 3-D structure of cytochrome P-450scc

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7 January 2021

Sterol 14 alpha-demethylase and its inhibition: structural considerations on interaction of azole antifungal agents with lanosterol 14 alpha-demethylase (P-450(14DM)) of yeast

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7 January 2021

10.1016/S0031-6865(97)00036-8

Identifiers

DOI

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10 November 2019

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