Aberrant methylation of the CDKN2a/p16INK4a gene promoter region in preinvasive bronchial lesions: a prospective study in high-risk patients without invasive cancer (Q74456126)

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scientific article published on 01 July 2002

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English	Aberrant methylation of the CDKN2a/p16INK4a gene promoter region in preinvasive bronchial lesions: a prospective study in high-risk patients without invasive cancer	scientific article published on 01 July 2002

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10 November 2019

Aberrant methylation of the CDKN2a/p16INK4a gene promoter region in preinvasive bronchial lesions: a prospective study in high-risk patients without invasive cancer (English)

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10 November 2019

invasive cancer

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Aude Lamy

1

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10 November 2019

Richard Sesboüé

2

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10 November 2019

Jeannette Bourguignon

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10 November 2019

Brigitte Dautréaux

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10 November 2019

Josette Métayer

5

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10 November 2019

Thierry Frébourg

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10 November 2019

Luc Thiberville

7

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10 November 2019

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1 July 2002

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10 November 2019

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International Journal of Cancer

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10 November 2019

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10 November 2019

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10 November 2019

189-193

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10 November 2019

Changes in bronchial epithelium in relation to cigarette smoking and in relation to lung cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Alterations of expression of Rb, p16(INK4A) and cyclin D1 in non-small cell lung carcinoma and their clinical significance.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Expression of p16 and lack of pRB in primary small cell lung cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Prognostic value of the immunohistochemical detection of p16INK4 expression in nonsmall cell lung carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Alterations of CDKN2 (p16) in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Intragenic mutations of the p16(INK4), p15(INK4B) and p18 genes in primary non-small-cell lung cancers

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Alterations of P16 (MTS1) in node-positive non-small cell lung carcinomas

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Disruption of the RB pathway and cell-proliferative activity in non-small-cell lung cancers.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Correlation between methylation status of the p16/CDKN2 gene and the expression of p16 and Rb proteins in primary non-small cell lung cancers.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Differential inactivation of CDKN2 and Rb protein in non-small-cell and small-cell lung cancer cell lines.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Frequent aberrant methylation of p16INK4a in primary rat lung tumors

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Localization of bronchial intraepithelial neoplastic lesions by fluorescence bronchoscopy.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Expansion of bronchial epithelial cell populations by in vitro culture of explants from dysplastic and histologically normal sites

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Characterization of PicoGreen reagent and development of a fluorescence-based solution assay for double-stranded DNA quantitation

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Hypermethylation of the caveolin-1 gene promoter in prostate cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Re: Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Hypermethylation at 9q32-33 tumour suppressor region is age-related in normal urothelium and an early and frequent alteration in bladder cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Differential frequencies of p16(INK4a) promoter hypermethylation, p53 mutation, and K-ras mutation in exfoliative material mark the development of lung cancer in symptomatic chronic smokers

1 reference

https://api.crossref.org/works/10.1002%2FIJC.10474

21 January 2018

Identifiers

10.1002/IJC.10474

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12115568%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12115568%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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