Functional analysis of CpG methylation in the BRCA1 promoter region (Q74460330)

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10 November 2019

title

Functional analysis of CpG methylation in the BRCA1 promoter region (English)

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10 November 2019

4

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10 November 2019

author name string

DiNardo DN

1

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10 November 2019

Butcher DT

2

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10 November 2019

Robinson DP

3

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10 November 2019

Rodenhiser DI

5

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10 November 2019

language of work or name

English

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publication date

1 August 2001

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10 November 2019

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10 November 2019

volume

20

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10 November 2019

issue

38

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10 November 2019

page(s)

5331-5340

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204697

10 November 2019

exact match

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GA-binding protein alpha/beta is a critical regulator of the BRCA1 promoter

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Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics

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Demethylation of the progesterone receptor CpG island is not required for progesterone receptor gene expression

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Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer

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BRCA1 required for transcription-coupled repair of oxidative DNA damage

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Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

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FMR1 enhancer is regulated by cAMP through a cAMP-responsive element.

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Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

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Cancer epigenetics comes of age

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Constitutively methylated CpG dinucleotides as mutation hot spots in the retinoblastoma gene (RB1).

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CpG methylation within the 5' regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site

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Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors

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5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

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7 January 2021

Tissue-specific methylation occurs in the essential promoter element of the tyrosine hydroxylase gene

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7 January 2021

CpG methylation, chromatin structure and gene silencing-a three-way connection

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Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells

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7 January 2021

Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter

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7 January 2021

Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens

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Homonucleotide tracts, short repeats and CpG/CpNpG motifs are frequent sites for heterogeneous mutations in the neurofibromatosis type 1 (NF1) tumour-suppressor gene

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Association of BRCA1 with Rad51 in mitotic and meiotic cells

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A Collaborative Survey of 80 Mutations in the BRCA1 Breast and Ovarian Cancer Susceptibility Gene

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Transcription of BRCA1 is dependent on the formation of a specific protein-DNA complex on the minimal BRCA1 Bi-directional promoter

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7 January 2021

Positive regulation of the BRCA1 promoter

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7 January 2021

Complex regulation of the BRCA1 gene.

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