Immunological adjuvants efficiently induce antigen-specific T cell responses in old mice: implications for vaccine adjuvant development in aged individuals (Q74523047)

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scientific article published on 01 January 2002

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English	Immunological adjuvants efficiently induce antigen-specific T cell responses in old mice: implications for vaccine adjuvant development in aged individuals	scientific article published on 01 January 2002

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scholarly article

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11 November 2019

Immunological adjuvants efficiently induce antigen-specific T cell responses in old mice: implications for vaccine adjuvant development in aged individuals (English)

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11 November 2019

immunologic adjuvant

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Thomas G Forsthuber

6

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11 November 2019

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Monika B Ebhardt

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11 November 2019

Carey L Shive

2

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11 November 2019

Rocio Guardia

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11 November 2019

Laurent Gapin

4

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11 November 2019

Bernhard O Boehm

5

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11 November 2019

publication date

1 January 2002

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11 November 2019

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11

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Cellular Immunology

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11 November 2019

215

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11 November 2019

1

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11 November 2019

87-97

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11 November 2019

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The immune system evolved to discriminate infectious nonself from noninfectious self

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Interleukin 2, interleukin 2 receptor, and interferon-gamma synthesis and mRNA expression in phorbol myristate acetate and calcium ionophore A23187-stimulated T cells from elderly humans

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Age-related impaired proliferation of peripheral blood mononuclear cells is associated with an increase in both IL-10 and IL-12.

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7 January 2021

Age-related impairment of early and late events of signal transduction in mouse immune cells

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7 January 2021

The effect of aging on the induction of humoral and cellular immunity and tolerance in two long-lived mouse strains.

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Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice

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Age-related alteration of cytokine production profile by T cell subsets in mice: a flow cytometric study

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7 January 2021

Altered Th1/Th2 commitment in human CD4+ T cells with ageing.

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7 January 2021

Age-related defects in Th1 and Th2 cytokine production by human T cells can be dissociated from altered frequencies of CD45RA+ and CD45RO+ T cell subsets.

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7 January 2021

Cell proliferation and cytokine production by CD4+ cells from old mice

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Early activation defects in T lymphocytes from aged mice

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Single-cytokine-producing CD4 memory cells predominate in type 1 and type 2 immunity

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T cell receptor complementarity determining region 3 length analysis reveals the absence of a characteristic public T cell repertoire in neonatal tolerance. The response in the "tolerant" mouse within the residual repertoire is quantitatively simila

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7 January 2021

Effect of aging on T lymphocyte activation

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Single-cell analyses reveal two defects in peptide-specific activation of naive T cells from aged mice

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The immune system in the elderly: II. Specific cellular immunity.

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7 January 2021

Changes in the aging immune system.

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7 January 2021

Age-related changes in T cell surface markers: a longitudinal analysis in genetically heterogeneous mice.

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Mature murine B and T cells transferred to SCID mice can survive indefinitely and many maintain a virgin phenotype

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10.1016/S0008-8749(02)00005-9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12142040%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12142040%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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