CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration (Q74528310)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10050880%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration (English)

1 reference

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11 November 2019

1 reference

Okamoto I

1

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11 November 2019

Kawano Y

2

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11 November 2019

Tsuiki H

3

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11 November 2019

Sasaki J

4

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11 November 2019

Nakao M

5

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11 November 2019

Matsumoto M

6

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11 November 2019

Suga M

7

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11 November 2019

Ando M

8

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11 November 2019

Nakajima M

9

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11 November 2019

Saya H

10

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11 November 2019

language of work or name

English

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publication date

1 February 1999

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11 November 2019

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11 November 2019

volume

18

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11 November 2019

issue

7

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11 November 2019

page(s)

1435-1446

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1202447

11 November 2019

exact match

0 references

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CD44 is the principal cell surface receptor for hyaluronate

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Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronan

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Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.

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A human lymphocyte homing receptor, the hermes antigen, is related to cartilage proteoglycan core and link proteins

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Early detachment of colon carcinoma cells during CD95(APO-1/Fas)-mediated apoptosis. I. De-adhesion from hyaluronate by shedding of CD44.

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Membrane protein secretases

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Glycosylation of CD44 negatively regulates its recognition of hyaluronan

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7 January 2021

Cell migration: a physically integrated molecular process

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Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation

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Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

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Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

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Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons

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Remodeling of glycoconjugates on CD44 enhances cell adhesion to hyaluronate, tumor growth and metastasis in B16 melanoma cells expressing beta1,4-N-acetylglucosaminyltransferase III.

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7 January 2021

Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity

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