Rapid drug metabolite profiling using fast liquid chromatography, automated multiple-stage mass spectrometry and receptor-binding (Q74592404)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

Rapid drug metabolite profiling using fast liquid chromatography, automated multiple-stage mass spectrometry and receptor-binding (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

author name string

H K Lim

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

S Stellingweif

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

S Sisenwine

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

K W Chan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

language of work or name

English

0 references

publication date

1 January 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

Journal of Chromatography

11 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

831

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

227-241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

Identifying small-molecule lead compounds: the screening approach to drug discovery

11 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Recent advances in the generation of chemical diversity libraries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Design of drugs through a consideration of drug metabolism and pharmacokinetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Simultaneous pharmacokinetic screening of a mixture of compounds in the dog using API LC/MS/MS analysis for increased throughput

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

A direct technique for the simultaneous determination of 10 drug candidates in plasma by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry interfaced to a Prospekt solid-phase extraction system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Plasma-pooling methods to increase throughput for in vivo pharmacokinetic screening

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Measurement of liver microsomal cytochrome p450 (CYP2D6) activity using [O-methyl-14C]dextromethorphan

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Sampling and extra-column effects in high-performance liquid chromatography; influence of peak skew on plate count calculations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Clinical pharmacokinetics of endocrine agents used in advanced breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

A mechanistic hypothesis for DNA adduct formation by tamoxifen following hepatic oxidative metabolism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Tandem reflectron time-of-flight mass spectrometer utilizing photodissociation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Affinity selection and mass spectrometry-based strategies to identify lead compounds in combinatorial libraries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Pulsed ultrafiltration mass spectrometry: a new method for screening combinatorial libraries.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Immunoaffinity Ultrafiltration with Ion Spray HPLC/MS for Screening Small-Molecule Libraries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Active drug metabolites. An overview of their relevance in clinical pharmacokinetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Relevance of genetic polymorphism in drug metabolism in the development of new drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

Comparative binding affinities of tamoxifen, 4-hydroxytamoxifen, and desmethyltamoxifen for estrogen receptors isolated from human breast carcinoma: correlation with blood levels in patients with metastatic breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

The metabolism of tamoxifen (I.C.I. 46,474). II. In female patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

The relationship between estrogenic action and chemical constitution in a group of azomethine derivatives

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2898%2900956-X

10.1016/S0021-9673(98)00956-X

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10070764%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference