In vivo activated T cells in rheumatoid synovitis. Analysis of Th1- and Th2-type cytokine production at clonal level in different stages of disease (Q74666178)

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scientific article published on 01 September 2002

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English	In vivo activated T cells in rheumatoid synovitis. Analysis of Th1- and Th2-type cytokine production at clonal level in different stages of disease	scientific article published on 01 September 2002

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scholarly article

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12 November 2019

In vivo activated T cells in rheumatoid synovitis. Analysis of Th1- and Th2-type cytokine production at clonal level in different stages of disease (English)

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12 November 2019

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R Gerli

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12 November 2019

author name string

O Bistoni

2

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12 November 2019

A Russano

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12 November 2019

S Fiorucci

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12 November 2019

L Borgato

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12 November 2019

M E F Cesarotti

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12 November 2019

C Lunardi

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12 November 2019

publication date

1 September 2002

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12 November 2019

Clinical and Experimental Immunology

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12 November 2019

129

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12 November 2019

3

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12 November 2019

549-555

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12 November 2019

Antiinflammatory and immunoregulatory action of methotrexate in the treatment of rheumatoid arthritis: evidence of increased interleukin-4 and interleukin-10 gene expression demonstrated in vitro by competitive reverse transcriptase-polymerase chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of interferon gamma- and interleukin-4-producing T cells in synovial fluid and peripheral blood of arthritis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Change in the Th1/Th2 phenotype of memory T-cell clones from rheumatoid arthritis synovium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with monoclonal anti-tumor necrosis factor alpha antibody results in an accumulation of Th1 CD4+ T cells in the peripheral blood of patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble CD30 in early rheumatoid arthritis as a predictor of good response to second-line therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced expression of the regulatory CD4+ T cell subset is related to Th1/Th2 balance and disease severity in rheumatoid arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response to methotrexate in early rheumatoid arthritis is associated with a decrease of T cell derived tumour necrosis factor alpha, increase of interleukin 10, and predicted by the initial concentration of interleukin 4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD30+ T cells in rheumatoid synovitis: mechanisms of recruitment and functional role

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are T cells in rheumatoid synovium aggressors or bystanders?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Th1 and Th2 cytokines expressing CD4+ and CD8+ T cells in rheumatoid arthritis by flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell trafficking into sites of inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathophysiology and treatment of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of T cells in the immunopathogenesis of rheumatoid arthritis: new perspectives

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN-gamma secreting TH1 cells in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Th1/Th2 paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion in vivo from an early dominant Th0/Th1 response to a Th2 phenotype during the development of collagen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synovial fluid T cell clones from oligoarticular juvenile arthritis patients display a prevalent Th1/Th0-type pattern of cytokine secretion irrespective of immunophenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is one year early, or too late? Comment on the article by Tak et al

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are differences in interleukin 10 production associated with joint damage?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Skewed T-cell receptor variable gene usage in the synovium of early and chronic rheumatoid arthritis patients and persistence of clonally expanded T cells in a chronic patient

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of different subsets of T regulatory cells in controlling autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine, activation marker, and chemokine receptor expression by individual CD4(+) memory T cells in rheumatoid arthritis synovium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th1/Th2 cytokine balance in arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine pathways and joint inflammation in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CD30+ T cells in rheumatoid arthritis: a counter-regulatory paradigm for Th1-driven diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+CD25+ T-cell development is regulated by at least 2 distinct mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synovitis of recent onset. A clinicopathologic study during the first month of disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rheumatoid arthritis: a disease of T-lymphocyte/macrophage immunoregulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular immunohistopathology of acute, subacute, and chronic synovitis in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A γ-chain complex forms a functional receptor on cloned human lymphocytes with natural killer-like activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient propagation and cloning of human T cells in the absence of antigen by means of OKT3, interleukin 2, and antigen-presenting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell immunoregulation in rheumatoid synovitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD8+CD11b+ peripheral blood T lymphocytes contain lymphokine-activated killer cell precursors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How important are T cells in chronic rheumatoid synovitis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation pathways of synovial T lymphocytes. Expression and function of the UM4D4/CDw60 antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diversity of rheumatoid synovial tissue T cells by T cell receptor analysis. Oligoclonal expansion in interleukin-2-responsive cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cells cloned from human rheumatoid synovial membrane functionally represent the Th1 subset

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of immunity to parasites by T cells and T cell-derived cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological properties of interleukin 10

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-10.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intrinsic migratory capacity of memory T cells contributes to their accumulation in rheumatoid synovium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rheumatoid inflammatory T-cell clones express mostly Th1 but also Th2 and mixed (Th0-like) cytokine patterns

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leucocyte-endothelial interactions and regulation of leucocyte migration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated interleukin-10 levels in patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High level of interleukin-10 production by the activated t cell population within the rheumatoid synovial membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-10 functions as an antiinflammatory cytokine in rheumatoid synovium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The method of deriving human T-cell clones alters the proportion of IL-10-producing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shift toward T lymphocytes with a T helper 1 cytokine-secretion profile in the joints of patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the synovial cell infiltrate in early rheumatoid synovial tissue in relation to local disease activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decrease in peripheral type 1 over type 2 T cell cytokine production in patients with rheumatoid arthritis correlates with an increase in severity of disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12197898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2249.2002.01913.X

1 reference

Europe PubMed Central

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12 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12197898%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

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