Cytosolic Ca2+ triggers early afterdepolarizations and Torsade de Pointes in rabbit hearts with type 2 long QT syndrome (Q74695277)

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12 November 2019

title

Cytosolic Ca2+ triggers early afterdepolarizations and Torsade de Pointes in rabbit hearts with type 2 long QT syndrome (English)

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12 November 2019

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Bum-Rak Choi

1

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12 November 2019

Francis Burton

series ordinal

2

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12 November 2019

Guy Salama

series ordinal

3

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12 November 2019

language of work or name

English

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publication date

1 September 2002

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12 November 2019

published in

Journal of Physiology

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12 November 2019

volume

543

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12 November 2019

issue

Pt 2

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12 November 2019

page(s)

615-631

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Depressant effect of magnesium on early afterdepolarizations and triggered activity induced by cesium, quinidine, and 4-aminopyridine in canine cardiac Purkinje fibers

12 November 2019

cites work

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Mechanism of ventricular arrhythmias caused by increased dispersion of repolarization.

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Experimental electrophysiology and arrhythmogenicity. Anisotropy and ventricular tachycardia

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The cytosolic calcium transient modulates the action potential of rat ventricular myocytes

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Antiarrhythmic effects of potassium channel openers in rhythm abnormalities related to delayed repolarization

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Role of external Ca2+ and K+ in gating of cardiac delayed rectifier K+ currents

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Purkinje fibre-papillary muscle interaction in the genesis of triggered activity in a guinea pig model

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Spatial features of calcium transients during early and delayed afterdepolarizations

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12 December 2020

Mechanisms in simulated torsade de pointes

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12 December 2020

Magnesium and the heart: antiarrhythmic therapy with magnesium

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Proarrhythmic effects of the class III agent almokalant: importance of infusion rate, QT dispersion, and early afterdepolarisations

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Cycle-length effects on the initiation of simulated torsade de pointes

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12 December 2020

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12 December 2020

Optical mapping of repolarization and refractoriness from intact hearts.

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12 December 2020

Propagation of excitation-contraction coupling into ventricular myocytes

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12 December 2020

Local, stochastic release of Ca2+ in voltage-clamped rat heart cells: visualization with confocal microscopy

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12 December 2020

Spatial non-uniformities in [Ca2+]i during excitation-contraction coupling in cardiac myocytes

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12 December 2020

Ca2+ load of guinea-pig ventricular myocytes determines efficacy of brief Ca2+ currents as trigger for Ca2+ release.

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Nonstationary vortexlike reentrant activity as a mechanism of polymorphic ventricular tachycardia in the isolated rabbit heart.

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12 December 2020

Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence

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12 December 2020

Maps of optical action potentials and NADH fluorescence in intact working hearts

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12 December 2020

A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay K 8644.

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Magnesium suppression of early afterdepolarizations and ventricular tachyarrhythmias induced by cesium in dogs

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QTU prolongation and polymorphic ventricular tachyarrhythmias due to bradycardia-dependent early afterdepolarizations. Afterdepolarizations and ventricular arrhythmias

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Electrophysiologic substrate of torsade de pointes: dispersion of repolarization or early afterdepolarizations?

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12 December 2020

Computer model of current-induced early afterdepolarizations in guinea pig ventricular myocytes

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12 December 2020

The effect of flunarizine and ryanodine on acquired torsades de pointes arrhythmias in the intact canine heart

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12 December 2020

Proarrhythmic response to potassium channel blockade. Numerical studies of polymorphic tachyarrhythmias

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12 December 2020

Optical mapping reveals that repolarization spreads anisotropically and is guided by fiber orientation in guinea pig hearts

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12 December 2020

Role of calcium loading in early afterdepolarizations generated by Cs+ in canine and guinea pig Purkinje fibers

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12 December 2020

Extracellular potassium modulation of drug block of IKr. Implications for torsade de pointes and reverse use-dependence

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12 December 2020

Response of Ca(2+)-loaded, depolarized guinea pig myocytes to critically timed premature stimulations.

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12 December 2020

The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns

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12 December 2020

Diversity of early afterdepolarizations in guinea pig myocytes: spatial characteristics of intracellular Ca2+ concentration

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12 December 2020

Optical Mapping of Drug-Induced Polymorphic Arrhythmias and Torsade de Pointes in the Isolated Rabbit Heart

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12 December 2020

Computer model of electrophysiological instability in very small heterogeneous ventricular syncytia

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12 December 2020

Regional localization of ERG, the channel protein responsible for the rapid component of the delayed rectifier, K+ current in the ferret heart

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12 December 2020

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12 December 2020

Early afterdepolarizations produced by d,l-sotalol and clofilium

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12 December 2020

Electrophysiologic features of torsades de pointes: insights from a new isolated rabbit heart model

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12 December 2020

Fluorescence measurement of calcium transients in perfused rabbit heart using rhod 2

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12 December 2020

Cellular basis for QT dispersion.

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12 December 2020

Experimental models of torsade de pointes

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12 December 2020

Modulation of HERG potassium channels by extracellular magnesium and quinidine

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12 December 2020

Pause induced early afterdepolarizations in the long QT syndrome: a simulation study

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12 December 2020

Heterogeneous distribution of the two components of delayed rectifier K+ current: a potential mechanism of the proarrhythmic effects of methanesulfonanilideclass III agents

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12 December 2020

Simulated torsade de pointes--the role of conduction defects and mechanism of QRS rotation

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12 December 2020

Electrotonic suppression of early afterdepolarizations in isolated rabbit Purkinje myocytes.

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12 December 2020

Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: time to revise current concepts

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12 December 2020

Sarcoplasmic Reticulum Ca2+ Release Causes Myocyte Depolarization : Underlying Mechanism and Threshold for Triggered Action Potentials

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12 December 2020

Simultaneous maps of optical action potentials and calcium transients in guinea-pig hearts: mechanisms underlying concordant alternans

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12 December 2020

Ventricular tachycardia with 2 variable opposing foci

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12 December 2020

Merocyanine 540 as an Optical Probe of Transmembrane Electrical Activity in the Heart

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12 December 2020

"Torsade de pointes" tachycardia. Re-entry or focal activity?

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12 December 2020

Possible mechanisms of the arrhythmias in the long QT syndrome

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12 December 2020

Pharmacological response of quinidine induced early afterdepolarisations in canine cardiac Purkinje fibres: insights into underlying ionic mechanisms.

1 reference

12 December 2020

10.1113/JPHYSIOL.2002.024570

Identifiers

DOI

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12 November 2019

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