SB-239063, a potent and selective inhibitor of p38 map kinase: preclinical pharmacokinetics and species-specific reversible isomerization (Q77083294)

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2 December 2019

title

SB-239063, a potent and selective inhibitor of p38 map kinase: preclinical pharmacokinetics and species-specific reversible isomerization (English)

1 reference

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2 December 2019

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K W Ward

1

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2 December 2019

J W Proksch

2

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2 December 2019

L M Azzarano

3

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2 December 2019

K L Salyers

4

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2 December 2019

J E McSurdy-Freed

5

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2 December 2019

T M Molnar

6

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2 December 2019

M A Levy

7

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2 December 2019

B R Smith

8

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2 December 2019

publication date

1 September 2001

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2 December 2019

published in

Pharmaceutical Research

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2 December 2019

volume

18

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2 December 2019

issue

9

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2 December 2019

page(s)

1336-1344

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Sucralfate: pharmacokinetics, metabolism and selective binding to experimental gastric and duodenal ulcers in animals

2 December 2019

cites work

1 reference

12 December 2020

Interspecies comparison of acivicin pharmacokinetics

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12 December 2020

p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentials

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12 December 2020

Pharmacokinetics of rolipram in the rhesus and cynomolgus monkeys, the rat and the rabbit. Studies on species differences

1 reference

12 December 2020

SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia.

1 reference

12 December 2020

Oral kinetics of dexfenfluramine and dexnorfenfluramine in non-human primates

1 reference

12 December 2020

Evaluation of the use of accelerated infusions for the determination of pharmacokinetic linearity.

1 reference

12 December 2020

Comparative pharmacokinetics of frusemide in female rhesus monkeys, cynomolgus monkeys and baboons

1 reference

12 December 2020

The trans-cis isomerization of trans-4'-(2-hydroxy-3,5-dibromo-benzylamino)cyclohexanol in vivo and in vitro in different species

1 reference

12 December 2020

Comparative pharmacokinetics of antipyrine (phenazone) in the baboon, cynomolgus monkey and rhesus monkey

1 reference

12 December 2020

SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence

1 reference

12 December 2020

Brain and plasma kinetics of the opioid 11C-hydromorphone in two macaque species

1 reference

12 December 2020

Inhibition of p38 MAP kinase as a therapeutic strategy

1 reference

12 December 2020

Preclinical pharmacokinetics of SB-203580, a potent inhibitor of p38 mitogen-activated protein kinase

1 reference

12 December 2020

The determination of essential clearance, volume, and residence time parameters of recirculating metabolic systems: the reversible metabolism of methylprednisolone and methylprednisone in rabbits

1 reference

12 December 2020

Interspecies comparison of the pharmacokinetics of aldose reductase inhibitors

1 reference

12 December 2020

Pharmacokinetics of Isosorbide Dinitrate in Rhesus Monkey, Cynomolgus Monkey, and Baboon

1 reference

12 December 2020

SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung

1 reference

12 December 2020

Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1013002414678

1 reference

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2 December 2019

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