Src-family kinase-p53/ Lyn p56 plays an important role in TNF-alpha-stimulated production of O2- by human neutrophils adherent to fibrinogen (Q77356871)

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scientific article published on 01 April 1999

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English	Src-family kinase-p53/ Lyn p56 plays an important role in TNF-alpha-stimulated production of O2- by human neutrophils adherent to fibrinogen	scientific article published on 01 April 1999

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10213272%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Src-family kinase-p53/ Lyn p56 plays an important role in TNF-alpha-stimulated production of O2- by human neutrophils adherent to fibrinogen (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10213272%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

author name string

S R Yan

1

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Europe PubMed Central

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5 December 2019

M J Novak

2

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5 December 2019

publication date

1 April 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10213272%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10213272%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

23

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5 December 2019

2

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Europe PubMed Central

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5 December 2019

167-178

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Europe PubMed Central

PubMed publication ID

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5 December 2019

https://scigraph.springernature.com/pub.10.1023/a:1020245129632

0 references

Endogenous reactive oxygen intermediates activate tyrosine kinases in human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of tumour necrosis factor alpha in vivo on human granulocyte oxidative metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

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Activity and activation of the granulocyte superoxide-generating system

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor and CD11/CD18 (beta 2) integrins act synergistically to lower cAMP in human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

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Chemoattractant signaling and leukocyte activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

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The short and happy life of neutrophil activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

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Activation of SRC family kinases in human neutrophils. Evidence that p58C-FGR and p53/56LYN redistributed to a Triton X-100-insoluble cytoskeletal fraction, also enriched in the caveolar protein caveolin, display an enhanced kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of granulocyte-macrophage colony-stimulating factor (CSF), granulocyte CSF, and tumor necrosis factor alpha in the priming of the neutrophil respiratory burst

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mac-1 (CD11b/CD18) mediates adherence-dependent hydrogen peroxide production by human and canine neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The src-family protein-tyrosine kinase p59hck is located on the secretory granules in human neutrophils and translocates towards the phagosome during cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of signals activating neutrophil functions by leukocyte integrins: LFA-1 and gp150/95, but not CR3, are able to stimulate the respiratory burst of human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Src family of tyrosine protein kinases in hemopoietic signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that tumor necrosis factor alpha (TNF)-induced activation of neutrophil respiratory burst on biologic surfaces is mediated by the p55 TNF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Priming of human neutrophil functions by tumor necrosis factor: enhancement of superoxide anion generation, degranulation, and chemotaxis to chemoattractants C5a and F-Met-Leu-Phe

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lyn, a src-like tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization of polymorphonuclear leukocytes by Porphyromonas (Bacteroides) gingivalis 381 in the absence of respiratory burst activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophils, host defense, and inflammation: a double-edged sword

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation, substrates and functions of src

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

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Microtubule integrity regulates src-like and extracellular signal-regulated kinase activities in human pro-monocytic cells. Importance for interleukin-1 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrins and signal transduction pathways: the road taken

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling by adhesion in human neutrophils: activation of the p72syk tyrosine kinase and formation of protein complexes containing p72syk and Src family kinases in neutrophils spreading over fibrinogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Chediak-Higashi syndrome: studies in four patients and a review of the literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor, other cytokines and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor triggers redistribution to a Triton X-100-insoluble, cytoskeletal fraction of beta 2 integrins, NADPH oxidase components, tyrosine phosphorylated proteins, and the protein tyrosine kinase p58fgr in human neutrophils adherent to

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular functions regulated by Src family kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of inhibitors of distinct signalling pathways on neutrophil Q2- generation in response to tumor necrosis factor-alpha, and antibodies against CD18 and CD11a: evidence for a common and unique pattern of sensitivity to wortmannin and protein ty

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

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Inflammatory cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of C-terminal Src kinase homologous kinase suppresses activation of Lyn tyrosine kinase required for VLA5-mediated Dami cell spreading

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein tyrosine kinases p53/56lyn and p72syk in MHC class I-mediated signal transduction in B lymphoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil activation by adhesion: mechanisms and pathophysiological implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-induced degranulation in adherent human neutrophils is dependent on CD11b/CD18-integrin-triggered oscillations of cytosolic free Ca2+

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A double-edged kinase Lyn: a positive and negative regulator for antigen receptor-mediated signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src family-selective tyrosine kinase inhibitor, PP1, inhibits both Fc epsilonRI- and Thy-1-mediated activation of rat basophilic leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil signal transduction and activation of the respiratory burst

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta 2 integrin-dependent tyrosine phosphorylation of paxillin in human neutrophils treated with tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular hyperpermeability induced by tumor necrosis factor and its augmentation by IL-1 and IFN-gamma is inhibited by selective depletion of neutrophils with a monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The production of cytokines by polymorphonuclear neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired tyrosine phosphorylation and Ca2+ mobilization, but not degranulation, in lyn-deficient bone marrow-derived mast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Syk activation is required for spreading and H2O2 release in adherent human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of p58c-fgr and p53/56lyn in adherent human neutrophils: evidence for a role of divalent cations in regulating neutrophil adhesion and protein tyrosine kinase activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue destruction by neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Priming of polymorphonuclear neutrophils by tumor necrosis factor alpha in whole blood: identification of two polymorphonuclear neutrophil subpopulations in response to formyl-peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta 2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple organ damage caused by tumor necrosis factor and prevented by prior neutrophil depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/10213272

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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