Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice (Q77470803)

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5 December 2019

title

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice (English)

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5 December 2019

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Z Hanna

1

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5 December 2019

D G Kay

2

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5 December 2019

N Rebai

3

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5 December 2019

A Guimond

4

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5 December 2019

S Jothy

5

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5 December 2019

P Jolicoeur

6

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5 December 2019

language of work or name

English

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publication date

1 October 1998

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5 December 2019

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5 December 2019

volume

95

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5 December 2019

page(s)

163-175

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5 December 2019

issue

2

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CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration.

5 December 2019

cites work

1 reference

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7 January 2021

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

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Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

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Survival from early, intermediate, and late stages of HIV infection

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Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

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Construction and in vitro properties of HIV-1 mutants with deletions in "nonessential" genes

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7 January 2021

Vacuolar myelopathy in transgenic mice expressing human immunodeficiency virus type 1 proteins under the regulation of the myelin basic protein gene promoter

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7 January 2021

Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity

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7 January 2021

Specific expression of the human CD4 gene in mature CD4+ CD8- and immature CD4+ CD8+ T cells and in macrophages of transgenic mice

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7 January 2021

Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease

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7 January 2021

From negative factor to a critical role in virus pathogenesis: the changing fortunes of Nef.

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Cardiomyopathy and other symptomatic heart diseases associated with HIV infection.

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Viral counts count in HIV infection

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The majority of cells infected with the defective murine AIDS virus belong to the B-cell lineage

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7 January 2021

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

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7 January 2021

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

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7 January 2021

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

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7 January 2021

Transgenic models of HIV-1.

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7 January 2021

The pharmacology of T cell apoptosis

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7 January 2021

Induction of cell differentiation by human immunodeficiency virus 1 vpr.

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7 January 2021

Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein

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7 January 2021

Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene

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7 January 2021

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

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7 January 2021

New concepts in the immunopathogenesis of HIV infection

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7 January 2021

Neurological complications of HIV infection

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7 January 2021

Acquired immunodeficiency syndrome and the kidney

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7 January 2021

Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

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7 January 2021

Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1.

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7 January 2021

Signal transduction by lymphocyte antigen receptors

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7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

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7 January 2021

10.1016/S0092-8674(00)81748-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9790524%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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