Alkylation-induced frameshift mutagenesis during in vitro DNA synthesis by DNA polymerases alpha and beta (Q77631492)

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7 December 2019

title

Alkylation-induced frameshift mutagenesis during in vitro DNA synthesis by DNA polymerases alpha and beta (English)

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7 December 2019

author name string

K A Eckert

series ordinal

1

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7 December 2019

S E Hile

series ordinal

2

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7 December 2019

language of work or name

English

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publication date

1 December 1998

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7 December 2019

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7 December 2019

volume

422

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7 December 2019

issue

2

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7 December 2019

page(s)

255-269

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Study of mutational specificity in the lacl gene of Escherichia coli as a window on the mechanisms of mutation

7 December 2019

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The role of adduct site-specific mutagenesis in understanding how carcinogen-DNA adducts cause mutations: perspective, prospects and problems

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Development and use of an in vitro HSV-tk forward mutation assay to study eukaryotic DNA polymerase processing of DNA alkyl lesions

7 January 2021

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Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis

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In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome

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Base alterations in yeast induced by alkylating agents with differing Swain-Scott substrate constants

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Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice

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Mutational spectrum at the Hprt locus in splenic T cells of B6C3F1 mice exposed to N-ethyl-N-nitrosourea

7 January 2021

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DNA sequence analysis of spontaneous and N-ethyl-N-nitrosourea-induced hprt mutations arising in vivo in cynomolgus monkey T-lymphocytes

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Molecular analysis of mutations induced in human cells by N-ethyl-N-nitrosourea

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Tissue-dependent enzyme-mediated repair or removal of O-ethyl pyrimidines and ethyl purines in carcinogen-treated rats

7 January 2021

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Replication of template-primers containing propanodeoxyguanosine by DNA polymerase beta. Induction of base pair substitution and frameshift mutations by template slippage and deoxynucleoside triphosphate stabilization

7 January 2021

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Oxygen radical induced mutagenesis is DNA polymerase specific.

7 January 2021

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Specificity of mutations induced by N-methyl-N-nitrosourea in a cDNA of the hprt gene

7 January 2021

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3-Methyladenine mutagenesis under conditions of SOS induction in Escherichia coli

7 January 2021

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Influence of DNA repair by ada and ogt alkyltransferases on the mutational specificity of alkylating agents.

7 January 2021

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Microsatellite instability in cancer of the proximal colon

7 January 2021

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Incorporation of dA opposite N3-ethylthymidine terminates in vitro DNA synthesis.

7 January 2021

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In vitroDNA replication implicates O2-ethyldeoxythymidine in transversion mutagenesis by ethylating agents

7 January 2021

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Methylation-induced blocks to in vitro DNA replication

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recA-dependent and recA-independent N-ethyl-N-nitrosourea mutagenesis at a plasmid-encoded herpes simplex virus thymidine kinase gene in Escherichia coli

7 January 2021

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Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity

7 January 2021

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Synthesis and template properties of an ethyl phosphotriester modified decadeoxyribonucleotide.

7 January 2021

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Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

7 January 2021

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Both O4-methylthymine and O4-ethylthymine preferentially form alkyl T.G pairs that do not block in vitro replication in a defined sequence.

7 January 2021

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7 January 2021

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7 January 2021

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Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts

7 January 2021

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Spectrum of point mutations in the coding region of the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene in human T-lymphocytes in vivo.

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

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7 December 2019

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