The pathogenesis of polycystic ovary syndrome: lessons from ovarian stimulation studies (Q77694083)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9856411%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

review article

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title

The pathogenesis of polycystic ovary syndrome: lessons from ovarian stimulation studies (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9856411%20AND%20SRC:MED&resulttype=core&format=json

polycystic ovary syndrome

7 December 2019

main subject

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1 reference

R B Barnes

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9856411%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

publication date

1 October 1998

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9856411%20AND%20SRC:MED&resulttype=core&format=json

Journal of Endocrinological Investigation

7 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9856411%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

volume

21

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9856411%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

issue

9

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7 December 2019

page(s)

567-579

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https://scigraph.springernature.com/pub.10.1007/bf03350782

7 December 2019

exact match

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cites work

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Restored insulin sensitivity but persistently increased early insulin secretion after weight loss in obese women with polycystic ovary syndrome

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Ovarian 17-hydroxyprogesterone hyperresponsiveness to gonadotropin-releasing hormone (GnRH) agonist challenge in women with polycystic ovary syndrome is not mediated by luteinizing hormone hypersecretion: evidence from GnRH agonist and human chorion

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Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion.

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Pituitary-ovarian responses to leuprolide acetate testing in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

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Insulin resistance in nonobese patients with polycystic ovarian disease

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Growth factors and polycystic ovarian syndrome

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Dysregulation of cytochrome P450c 17 alpha as the cause of polycystic ovarian syndrome

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12 December 2020

Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis

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Current concepts of polycystic ovary syndrome

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Insulin insensitivity in adrenal hyperplasia due to nonclassical steroid 21-hydroxylase deficiency

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Ovarian follicle atresia: a hormonally controlled apoptotic process

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12 December 2020

Ovarian steroidogenic responses to gonadotropin-releasing hormone agonist testing with nafarelin in hirsute women with adrenal responses to adrenocorticotropin suggestive of 3 beta-hydroxy-delta 5-steroid dehydrogenase deficiency

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12 December 2020

Androgen responses to acutely increased endogenous insulin levels in hyperandrogenic and normal cycling women

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12 December 2020

Polycystic ovary syndrome: evidence for reduced sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone

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12 December 2020

Growth factors in normal ovarian follicle development

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12 December 2020

Development of hyperandrogenism during treatment with insulin-like growth factor-I (IGF-I) in female patients with Laron syndrome

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Control of immunoactive inhibin production by human granulosa cells

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Primary amenorrhoea and infertility due to a mutation in the beta-subunit of follicle-stimulating hormone

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Heterodimers and homodimers of inhibin subunits have different paracrine action in the modulation of luteinizing hormone-stimulated androgen biosynthesis

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12 December 2020

Pituitary-ovarian responses to nafarelin testing in the polycystic ovary syndrome

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12 December 2020

The polycystic ovary syndrome: pathogenesis and treatment

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12 December 2020

The impact of insulin secretion on the ovarian response to exogenous gonadotropins in polycystic ovary syndrome

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12 December 2020

Enhanced early insulin response to glucose in relation to insulin resistance in women with polycystic ovary syndrome and normal glucose tolerance

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12 December 2020

Resistance of gonadotropin releasing hormone drive to sex steroid-induced suppression in hyperandrogenic anovulation.

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Testosterone, a follicular regulator: key to anovulation

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Postpubertal outcome in girls diagnosed of premature pubarche during childhood: increased frequency of functional ovarian hyperandrogenism

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12 December 2020

Accelerated 24-hour luteinizing hormone pulsatile activity in adolescent girls with ovarian hyperandrogenism: relevance to the developmental phase of polycystic ovarian syndrome

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12 December 2020

A pilot study of the human chorionic gonadotrophin test for ovarian hyperandrogenism

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12 December 2020

Mid-follicular phase pulses of inhibin B are absent in polycystic ovarian syndrome and are initiated by successful laparoscopic ovarian diathermy: a possible mechanism regulating emergence of the dominant follicle

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12 December 2020

17 beta-Oestradiol, androstenedione and inhibin levels in fluid from individual follicles of normal and polycystic ovaries, and in ovaries from androgen treated female to male transsexuals

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12 December 2020

Suppression of serum insulin by diazoxide reduces serum testosterone levels in obese women with polycystic ovary syndrome

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12 December 2020

Localization of androgen receptor in the follicle and corpus luteum of the primate ovary during the menstrual cycle

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12 December 2020

Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome

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12 December 2020

Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome

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12 December 2020

Isolated deficiency of follicle-stimulating hormone. Clinical and laboratory features

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12 December 2020

The role of adrenal hyperandrogenism, insulin resistance, and obesity in the pathogenesis of polycystic ovarian syndrome.

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12 December 2020

The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome.

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The android woman--a risky condition

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12 December 2020

Adrenal androgen excess in women: lack of a role for 17-hydroxylase and 17,20-lyase dysregulation

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12 December 2020

Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries

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12 December 2020

Estradiol production by granulosa cells of normal and polycystic ovaries: relationship to menstrual cycle history and concentrations of gonadotropins and sex steroids in follicular fluid

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12 December 2020

Evidence for insulin resistance in nonobese patients with polycystic ovarian disease

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12 December 2020

Role of androgens in follicle maturation and atresia

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12 December 2020

Serum alpha-inhibin levels in polycystic ovary syndrome: relationship to the serum androstenedione level

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12 December 2020

Diagnosis and therapy of hyperandrogenism

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12 December 2020

Modulation by insulin of follicle-stimulating hormone and luteinizing hormone actions in human granulosa cells of normal and polycystic ovaries

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12 December 2020

The effects of a gonadotrophin-releasing hormone agonist on treatment with low dose follicle stimulating hormone in polycystic ovary syndrome

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12 December 2020

Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome

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12 December 2020

Hormonal effects of flutamide in young women with polycystic ovary syndrome

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12 December 2020

High ovarian response in Yoruba African women during ovulation induction for assisted conception.

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12 December 2020

Ovarian hyperandrogynism as a result of congenital adrenal virilizing disorders: evidence for perinatal masculinization of neuroendocrine function in women

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12 December 2020

Hyperinsulinemia and decreased insulin-like growth factor-binding protein-1 are common features in prepubertal and pubertal girls with a history of premature pubarche.

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12 December 2020

Inhibitory effect of sandostatin on secretion of luteinising hormone and ovarian steroids in polycystic ovary syndrome

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12 December 2020

Pathogenesis and treatment of polycystic ovary syndrome

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12 December 2020

Insulin, somatotropic, and luteinizing hormone axes in lean and obese women with polycystic ovary syndrome: common and distinct features

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12 December 2020

Evidence for a primary abnormality of thecal cell steroidogenesis in the polycystic ovary syndrome

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12 December 2020

Clinical and hormonal characteristics of obese amenorrheic hyperandrogenic women before and after weight loss

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12 December 2020

Decreased insulin sensitivity in prepubertal girls with premature adrenarche and acanthosis nigricans.

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12 December 2020

Gonadotrophin and gonadal steroid response to a single dose of a long-acting agonist of gonadotrophin-releasing hormone in ovulatory and anovulatory women with polycystic ovary syndrome

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12 December 2020

Developmental and hormonal regulation of rat theca-cell differentiation factor secretion in ovarian follicles

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12 December 2020

Normal basal and insulin-stimulated fuel metabolism in lean women with the polycystic ovary syndrome.

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12 December 2020

Ultrasonographic appearance of polycystic ovaries is associated with exaggerated ovarian androgen and oestradiol responses to gonadotrophin-releasing hormone agonist in women undergoing assisted reproduction treatment.

1 reference

12 December 2020

Pulsatile gonadotrophin secretion in women with polycystic ovary syndrome after gonadotrophin-releasing hormone agonist treatment

1 reference

12 December 2020

Pathophysiology of ovarian steroid secretion in polycystic ovary syndrome

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12 December 2020

17 alpha-Hydroxyprogesterone responses to leuprolide and serum androgens in obese women with and without polycystic ovary syndrome offer dietary weight loss

1 reference

12 December 2020

17-Hydroxyprogesterone response to buserelin testing in the polycystic ovary syndrome

1 reference

12 December 2020

Current and future status of ovulation induction in polycystic ovary syndrome

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12 December 2020

Insulin infusion amplifies 17 alpha-hydroxycorticosteroid intermediates response to adrenocorticotropin in hyperandrogenic women: apparent relative impairment of 17,20-lyase activity

1 reference

12 December 2020

Effect of recombinant activin on androgen synthesis in cultured human thecal cells

1 reference

12 December 2020

Characterization of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance, and/or hyperinsulinemia

1 reference

12 December 2020

Detection of Functional Ovarian Hyperandrogenism in Women with Androgen Excess

1 reference

12 December 2020

Combined luteinizing hormone releasing hormone analogue and exogenous gonadotrophins for the treatment of infertility associated with polycystic ovaries

1 reference

12 December 2020

Ovarian thecal/interstitial androgen synthesis is enhanced by a follicle-stimulating hormone-stimulated paracrine mechanism

1 reference

12 December 2020

Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome

1 reference

12 December 2020

Studies of the nature of 17-hydroxyprogesterone hyperresonsiveness to gonadotropin-releasing hormone agonist challenge in functional ovarian hyperandrogenism

1 reference

12 December 2020

How common are polycystic ovaries in normal women and what is their significance for the fertility of the population?

1 reference

12 December 2020

Insulin sensitivity in women with polycystic ovary syndrome: relationship to hyperandrogenemia

1 reference

12 December 2020

Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome

1 reference

12 December 2020

Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome

1 reference

12 December 2020

Serine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndrome

1 reference

12 December 2020

5' polymorphism of the CYP17 gene is not associated with serum testosterone levels in women with polycystic ovaries

1 reference

12 December 2020

Evidence that idiopathic functional adrenal hyperandrogenism is caused by dysregulation of adrenal steroidogenesis and that hyperinsulinemia may be involved

1 reference

12 December 2020

Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03350782

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9856411%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 December 2019

0 references

1 reference