Contribution of the two Gs-coupled PGE2-receptors EP2-receptor and EP4-receptor to the inhibition by PGE2 of the LPS-induced TNFalpha-formation in Kupffer cells from EP2-or EP4-receptor-deficient mice. Pivotal role for the EP4-receptor in wild type (Q77697146)

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scientific article published on 01 March 2002

Language	Label	Description	Also known as
English	Contribution of the two Gs-coupled PGE2-receptors EP2-receptor and EP4-receptor to the inhibition by PGE2 of the LPS-induced TNFalpha-formation in Kupffer cells from EP2-or EP4-receptor-deficient mice. Pivotal role for the EP4-receptor in wild type	scientific article published on 01 March 2002

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scholarly article

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Europe PubMed Central

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7 December 2019

Contribution of the two Gs-coupled PGE2-receptors EP2-receptor and EP4-receptor to the inhibition by PGE2 of the LPS-induced TNFalpha-formation in Kupffer cells from EP2-or EP4-receptor-deficient mice. Pivotal role for the EP4-receptor in wild type Kupffer cells (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11867175%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

author name string

Alexandra Fennekohl

1

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7 December 2019

Yukihiko Sugimoto

2

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7 December 2019

Eri Segi

3

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7 December 2019

Takayuki Maruyama

4

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7 December 2019

Atsushi Ichikawa

5

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7 December 2019

Gerhard P Püschel

6

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7 December 2019

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1 March 2002

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7 December 2019

Journal of Hepatology

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7 December 2019

36

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7 December 2019

3

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7 December 2019

328-334

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7 December 2019

Identification of prostaglandin D2 as the major eicosanoid from liver endothelial and Kupffer cells

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Stimulation of glycogen phosphorylase in rat hepatocytes via prostanoid release from Kupffer cells by recombinant rat anaphylatoxin C5a but not by native human C5a in hepatocyte/Kupffer cell co-cultures

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Increase in prostanoid formation in rat liver macrophages (Kupffer cells) by human anaphylatoxin C3a

1 reference

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7 January 2021

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Glycogenolytic and antiglycogenolytic prostaglandin E2 actions in rat hepatocytes are mediated via different signalling pathways

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Inhibitory Effect of Prostaglandins on the Stimulation by Glucagon and Adrenaline of Formation of Cyclic AMP in Rat Hepatocytes

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Inhibition by PGE2 of glucagon-induced increase in phosphoenolpyruvate carboxykinase mRNA and acceleration of mRNA degradation in cultured rat hepatocytes

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Increase by anaphylatoxin C5a of glucose output in perfused rat liver via prostanoids derived from nonparenchymal cells: direct action of prostaglandins and indirect action of thromboxane A(2) on hepatocytes

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Induction by interleukin 6 of Gs-coupled prostaglandin E2 receptors in rat hepatocytes mediating a prostaglandin E2–dependent inhibition of the hepatocyte's acute phase response

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The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus

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7 January 2021

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Eicosanoid-mediated contractility of hepatic stellate cells

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7 January 2021

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Hepatic stellate cell contraction is inhibited by lipo-prostaglandin E1 in vitro.

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7 January 2021

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Timing of prostaglandin exposure is critical for the inhibition of LPS- or IFN-gamma-induced macrophage NO synthesis by PGE2.

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Interdependence of tumor necrosis factor, prostaglandin E2, and protein synthesis in lipopolysaccharide-exposed rat Kupffer cells.

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Prostaglandin E receptors

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Differential expression of prostanoid receptors in hepatocytes, Kupffer cells, sinusoidal endothelial cells and stellate cells of rat liver

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7 January 2021

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Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2)

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7 January 2021

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Patent ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient mice

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7 January 2021

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The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth.

1 reference

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7 January 2021

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Characterization of the LPS-stimulated expression of EP2 and EP4 prostaglandin E receptors in mouse macrophage-like cell line, J774.1.

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7 January 2021

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Exclusive expression of the Gs-linked prostaglandin E2 receptor subtype 4 mRNA in mononuclear Jurkat and KM-3 cells and coexpression of subtype 4 and 2 mRNA in U-937 cells

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Prostaglandin E2 receptors of the EP2 and EP4 subtypes downregulate tumor necrosis factor alpha-induced intercellular adhesion molecule-1 expression in human gingival fibroblasts

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Identifiers

10.1016/S0168-8278(01)00277-X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11867175%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11867175%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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