Quinolines as potent 5-lipoxygenase inhibitors: synthesis and biological profile of L-746,530 (Q77744563)

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8 December 2019

title

Quinolines as potent 5-lipoxygenase inhibitors: synthesis and biological profile of L-746,530 (English)

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8 December 2019

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D Dubé

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M Blouin

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C Brideau

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C C Chan

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S Desmarais

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D Ethier

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J P Falgueyret

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R W Friesen

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M Girard

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Y Girard

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J Guay

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D Riendeau

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P Tagari

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R N Young

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publication date

1 May 1998

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Bioorganic & Medicinal Chemistry Letters

8 December 2019

published in

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volume

8

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issue

10

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8 December 2019

page(s)

1255-1260

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Modulators of leukotriene biosynthesis and receptor activation

8 December 2019

cites work

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The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma

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Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses

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The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo

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7 January 2021

Substituted thiopyrano[2,3,4-c,d]indoles as potent, selective, and orally active inhibitors of 5-lipoxygenase. Synthesis and biological evaluation of L-691,816

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7 January 2021

Naphthalenic lignan lactones as selective, nonredox 5-lipoxygenase inhibitors. Synthesis and biological activity of (methoxyalkyl)thiazole and methoxytetrahydropyran hybrids.

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7 January 2021

Dioxabicyclooctanyl naphthalenenitriles as nonredox 5-lipoxygenase inhibitors: structure-activity relationship study directed toward the improvement of metabolic stability

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7 January 2021

Substituted (pyridylmethoxy)naphthalenes as potent and orally active 5-lipoxygenase inhibitors; synthesis, biological profile, and pharmacokinetics of L-739,010.

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7 January 2021

Characterization of the arachidonate and ATP binding sites of human 5-lipoxygenase using photoaffinity labeling and enzyme immobilization

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7 January 2021

Nickel-Phosphine Complex-Catalyzed Grignard Coupling. I. Cross-Coupling of Alkyl, Aryl, and Alkenyl Grignard Reagents with Aryl and Alkenyl Halides: General Scope and Limitations

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7 January 2021

10.1016/S0960-894X(98)00201-7

Identifiers

DOI

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8 December 2019

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