Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading (Q77754821)

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8 December 2019

title

Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading (English)

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8 December 2019

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8 December 2019

Don W. Cleveland

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8 December 2019

author name string

W Ernest Lyons

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8 December 2019

Jian Liu

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8 December 2019

Thomas B Bartnikas

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Jeffrey Rothstein

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Donald L Price

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8 December 2019

Jonathan D Gitlin

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Philip C Wong

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8 December 2019

publication date

1 April 2002

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8 December 2019

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8 December 2019

volume

5

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8 December 2019

issue

4

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8 December 2019

page(s)

301-307

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

8 December 2019

cites work

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7 January 2021

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

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7 January 2021

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

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7 January 2021

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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7 January 2021

Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

1 reference

7 January 2021

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

7 January 2021

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

7 January 2021

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

7 January 2021

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

1 reference

7 January 2021

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

7 January 2021

ALS, SOD and peroxynitrite

1 reference

7 January 2021

Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase

1 reference

7 January 2021

The copper transporter CTR1 provides an essential function in mammalian embryonic development

1 reference

7 January 2021

Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development

1 reference

7 January 2021

Intracellular pathways of copper trafficking in yeast and humans

1 reference

7 January 2021

The copper chaperone for superoxide dismutase

1 reference

7 January 2021

Copper stabilizes a heterodimer of the yCCS metallochaperone and its target superoxide dismutase

1 reference

7 January 2021

Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase

1 reference

7 January 2021

41 Preparation and assay of superioxide dismutases

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7 January 2021

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

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7 January 2021

Cognitive decline strongly correlates with cortical atrophy in Alzheimer's dementia

1 reference

7 January 2021

Neuronal regeneration enhances the expression of the immunophilin FKBP-12

1 reference

7 January 2021

Toxicity of ALS-linked SOD1 mutants

1 reference

7 January 2021

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

1 reference

7 January 2021

Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants

1 reference

7 January 2021

Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L.

1 reference

7 January 2021

Nitrotyrosination contributes minimally to toxicity of mutant SOD1 associated with ALS.

1 reference

7 January 2021

Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis.

1 reference

7 January 2021

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

1 reference

7 January 2021

A familial amyotrophic lateral sclerosis-associated A4V Cu, Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value.

1 reference

7 January 2021

Reexamination of the mechanism of hydroxyl radical adducts formed from the reaction between familial amyotrophic lateral sclerosis-associated Cu,Zn superoxide dismutase mutants and H2O2.

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7 January 2021

Evidence against the generation of free hydroxyl radicals from the interaction of copper,zinc-superoxide dismutase and hydrogen peroxide

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7 January 2021

Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis

1 reference

7 January 2021

Copper(2+) binding to the surface residue cysteine 111 of His46Arg human copper-zinc superoxide dismutase, a familial amyotrophic lateral sclerosis mutant

1 reference

7 January 2021

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

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7 January 2021

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

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7 January 2021

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

1 reference

7 January 2021

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

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7 January 2021

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

1 reference

7 January 2021

Formation of intermediate filament protein aggregates with disparate effects in two transgenic mouse models lacking the neurofilament light subunit

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7 January 2021

Persistent regional changes in brain copper, cuproenzymes and catecholamines following perinatal copper deficiency in mice

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7 January 2021

Identifiers

DOI

10.1038/NN823

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8 December 2019

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