Peptide ligands can bind to distinct sites in integrin alphaIIbbeta3 and elicit different functional responses (Q77841213)

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8 December 2019

title

Peptide ligands can bind to distinct sites in integrin alphaIIbbeta3 and elicit different functional responses (English)

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8 December 2019

5

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8 December 2019

author name string

C S Cierniewski

1

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8 December 2019

T Byzova

2

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8 December 2019

M Papierak

3

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8 December 2019

T A Haas

4

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8 December 2019

L Zhang

6

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8 December 2019

M Cieslak

7

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8 December 2019

E F Plow

8

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8 December 2019

language of work or name

English

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publication date

1 June 1999

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Journal of Biological Chemistry

8 December 2019

published in

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8 December 2019

volume

274

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8 December 2019

issue

24

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8 December 2019

page(s)

16923-16932

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Integrins: a family of cell surface receptors

8 December 2019

cites work

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Integrins: emerging paradigms of signal transduction

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Perspectives series: cell adhesion in vascular biology. Integrin signaling in vascular biology

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ADP-dependent common receptor mechanism for binding of von Willebrand factor and fibrinogen to human platelets

21 January 2018

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Inhibition of von Willebrand factor–platelet interaction by fibrinogen

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Fibrinogen, fibrinogen receptors, and the peptides that inhibit these interactions

21 January 2018

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Inhibition of von Willebrand factor binding to platelets by two recognition site peptides: the pentadecapeptide of the carboxy terminus of the fibrinogen gamma chain and the tetrapeptide arg-gly-asp-ser

21 January 2018

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A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation

21 January 2018

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Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).

21 January 2018

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Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins

21 January 2018

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Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor

21 January 2018

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The ligand recognition specificity of beta3 integrins

21 January 2018

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Microenvironmental changes in platelet membranes induced by the interaction of fibrinogen-derived peptide ligands with platelet integrins

21 January 2018

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Critical residues of integrin alphaIIb subunit for binding of alphaIIbbeta3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3).

21 January 2018

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Role of fibrinogen alpha and gamma chain sites in platelet aggregation

21 January 2018

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The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets

21 January 2018

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Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion receptors

21 January 2018

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Networking in the hemostatic system. Integrin alphaiibbeta3 binds prothrombin and influences its activation

21 January 2018

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Stimulation of platelet glycoprotein IIb-IIIa (alpha IIb beta 3-integrin) functional activity by a monoclonal antibody to the N-terminal region of glycoprotein IIIa

21 January 2018

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Europium(III) luminescence and tyrosine to terbium(III) energy-transfer studies of invertebrate (octopus) calmodulin

21 January 2018

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Fluorescence energy transfer analysis of calmodulin-peptide complexes

21 January 2018

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Preparation of suspensions of washed platelets from humans.

21 January 2018

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Characterization of non-peptide antagonist and peptide agonist binding sites of the NK1 receptor with fluorescent ligands

21 January 2018

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Demonstration of non-linear detection in ELISA resulting in up to 1000-fold too high affinities of fibrinogen binding to integrin alpha IIb beta 3

21 January 2018

1 reference

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Characterization of Cation-Binding Sequences in the Platelet Integrin GPIIb-IIIa (.alpha.IIb.beta.3) by Terbium Luminescence

21 January 2018

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Probing the structure and function of the tachykinin neurokinin-2 receptor through biosynthetic incorporation of fluorescent amino acids at specific sites

21 January 2018

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Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

21 January 2018

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Ligand binding to integrin alphaIIbbeta3 is dependent on a MIDAS-like domain in the beta3 subunit

21 January 2018

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Molecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function

21 January 2018

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Molecular motion in spin-labeled phospholipids and membranes

21 January 2018

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Platelet GPIIb-IIIa blockers

21 January 2018

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Site-directed mutagenesis of the cell-binding domain of human fibronectin: separable, synergistic sites mediate adhesive function.

21 January 2018

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Mutation of putative divalent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin

21 January 2018

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Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

21 January 2018

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An allosteric Ca2+ binding site on the beta3-integrins that regulates the dissociation rate for RGD ligands

21 January 2018

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Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin

21 January 2018

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Evidence that the integrin beta3 and beta5 subunits contain a metal ion-dependent adhesion site-like motif but lack an I domain

21 January 2018

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Ligand binding to GPIIb-IIIa: a status report

21 January 2018

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Ligand and cation binding are dual functions of a discrete segment of the integrin β3 subunit: Cation displacement is involved in ligand binding

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.24.16923

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10358039%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference