The structure, catalytic mechanism and regulation of adenylyl cyclase (Q77892151)

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9 December 2019

review article

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title

The structure, catalytic mechanism and regulation of adenylyl cyclase (English)

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9 December 2019

1

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9 December 2019

author name string

S R Sprang

series ordinal

2

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9 December 2019

publication date

1 December 1998

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Current Opinion in Structural Biology

9 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9914249%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

volume

8

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9 December 2019

issue

6

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9 December 2019

page(s)

713-719

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Complexity and diversity of mammalian adenylyl cyclases

9 December 2019

cites work

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7 January 2021

Conversion of forskolin-insensitive to forskolin-sensitive (mouse-type IX) adenylyl cyclase

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7 January 2021

Two distinct adenosine-sensitive sites on adenylate cyclase

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7 January 2021

Isozyme-dependent sensitivity of adenylyl cyclases to P-site-mediated inhibition by adenine nucleosides and nucleoside 3'-polyphosphates.

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7 January 2021

The catalytic mechanism of mammalian adenylyl cyclase. Equilibrium binding and kinetic analysis of P-site inhibition

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7 January 2021

Voltage-sensitive adenylyl cyclase activity in cultured neurons. A calcium-independent phenomenon

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7 January 2021

Purification and characterization of a soluble form of mammalian adenylyl cyclase

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7 January 2021

Interaction of the two cytosolic domains of mammalian adenylyl cyclase

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7 January 2021

Two Cytoplasmic Domains of Mammalian Adenylyl Cyclase Form a G- and Forskolin-activated Enzymein Vitro

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7 January 2021

Identification of a Gialpha binding site on type V adenylyl cyclase

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7 January 2021

Three discrete regions of mammalian adenylyl cyclase form a site for Gsalpha activation.

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7 January 2021

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS

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7 January 2021

Genetic selection of mammalian adenylyl cyclases insensitive to stimulation by Gsalpha

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7 January 2021

Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits

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7 January 2021

A region of adenylyl cyclase 2 critical for regulation by G protein beta gamma subunits

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7 January 2021

Phosphorylation and inhibition of type III adenylyl cyclase by calmodulin-dependent protein kinase II in vivo

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7 January 2021

Adenylyl cyclase type II is stimulated by PKC via C-terminal phosphorylation

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7 January 2021

The calmodulin binding domain of nitric oxide synthase and adenylyl cyclase

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7 January 2021

Regulation of type I adenylyl cyclase by calmodulin kinase IV in vivo

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7 January 2021

Adenylyl cyclase 6 is selectively regulated by protein kinase A phosphorylation in a region involved in Galphas stimulation

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7 January 2021

Structure of the adenylyl cyclase catalytic core

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7 January 2021

Interaction of Gsalpha with the cytosolic domains of mammalian adenylyl cyclase

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7 January 2021

Interactions of forskolin and ATP with the cytosolic domains of mammalian adenylyl cyclase.

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7 January 2021

A polymerase I palm in adenylyl cyclase?

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7 January 2021

Phorbol ester-induced sensitisation of adenylyl cyclase type II is related to phosphorylation of threonine 1057.

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7 January 2021

Catalytic mechanism of the adenylyl and guanylyl cyclases: modeling and mutational analysis

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7 January 2021

Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases.

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7 January 2021

Two amino acid substitutions convert a guanylyl cyclase, RetGC-1, into an adenylyl cyclase.

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7 January 2021

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

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7 January 2021

2',5'-Dideoxyadenosine 3'-polyphosphates are potent inhibitors of adenylyl cyclases.

1 reference

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7 January 2021

Mutations uncover a role for two magnesium ions in the catalytic mechanism of adenylyl cyclase

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7 January 2021

Identification of functional domains of adenylyl cyclase using in vivo chimeras

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7 January 2021

The conserved asparagine and arginine are essential for catalysis of mammalian adenylyl cyclase

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7 January 2021

Protein kinase C alters the responsiveness of adenylyl cyclases to G protein alpha and betagamma subunits

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7 January 2021

10.1016/S0959-440X(98)80090-0

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9914249%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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