Effect of p21waf1/cip1 transgene on radiation induced apoptosis in T cells (Q77918828)

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9 December 2019

title

Effect of p21waf1/cip1 transgene on radiation induced apoptosis in T cells (English)

1 reference

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9 December 2019

author name string

Fotedar R

1

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9 December 2019

Brickner H

2

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9 December 2019

Saadatmandi N

3

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9 December 2019

Rousselle T

4

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9 December 2019

Diederich L

5

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9 December 2019

Munshi A

6

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9 December 2019

Jung B

7

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9 December 2019

Reed JC

8

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9 December 2019

Fotedar A

9

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9 December 2019

language of work or name

English

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publication date

1 June 1999

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9 December 2019

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9 December 2019

volume

18

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9 December 2019

issue

24

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9 December 2019

page(s)

3652-3658

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1202693

9 December 2019

exact match

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T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

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p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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Activation-induced T-cell death is cell cycle dependent and regulated by cyclin B.

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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