The protease-antiprotease battle in the cystic fibrosis lung (Q78204686)

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12 December 2019

review article

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title

The protease-antiprotease battle in the cystic fibrosis lung (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10472249%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

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I M Balfour-Lynn

1

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12 December 2019

publication date

1 January 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10472249%20AND%20SRC:MED&resulttype=core&format=json

Journal of the Royal Society of Medicine

12 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10472249%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

volume

92 Suppl 37

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12 December 2019

page(s)

23-30

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Pharmacokinetics of recombinant secretory leukoprotease inhibitor aerosolized to normals and individuals with cystic fibrosis

12 December 2019

cites work

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12 December 2020

High incidence of primary pulmonary hypertension associated with appetite suppressants in Belgium

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12 December 2020

Leukotriene B4 markedly elevated in the epithelial lining fluid of patients with cystic fibrosis

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12 December 2020

Transgenic livestock as bioreactors: stable expression of human alpha-1-antitrypsin by a flock of sheep

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12 December 2020

Recombinant secretory leukoprotease inhibitor augments glutathione levels in lung epithelial lining fluid

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12 December 2020

Interleukin-8 Concentrations Are Elevated in Bronchoalveolar Lavage, Sputum, and Sera of Children with Cystic Fibrosis

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12 December 2020

Rapid inactivation of alpha1-protease inhibitor (alpha1-antitrypsin) by elastase

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12 December 2020

Protease phenotypes of Pseudomonas aeruginosa isolated from patients with cystic fibrosis.

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12 December 2020

Longitudinal study of immune response to Pseudomonas aeruginosa antigens in cystic fibrosis

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12 December 2020

Ultrastructural localization of bronchial antileukoprotease in central and peripheral human airways by a gold-labeling technique using monoclonal antibodies

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12 December 2020

Complement activation in cystic fibrosis respiratory fluids: in vivo and in vitro generation of C5a and chemotactic activity

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12 December 2020

Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema

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12 December 2020

Fibronectin-cleaving activity in bronchial secretions of patients with cystic fibrosis

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12 December 2020

Granulocyte elastase-mediated proteolysis of alpha 1-antitrypsin in cystic fibrosis bronchopulmonary secretions

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12 December 2020

Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor

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12 December 2020

Aerosol α1 -antitrypsin treatment for cystic fibrosis

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12 December 2020

Protease actions on airway secretions. Relevance to cystic fibrosis

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12 December 2020

High level expression of active human alpha-1-antitrypsin in the milk of transgenic sheep

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12 December 2020

Human neutrophil elastase and elastase/alpha 1-antiprotease complex in cystic fibrosis. Comparison with interstitial lung disease and evaluation of the effect of intravenously administered antibiotic therapy

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12 December 2020

Consequences of unbalanced protease in the lung: protease involvement in destruction and local defense mechanisms of the lung

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12 December 2020

Different Susceptibility of Elastase Inhibitors to Inactivation by Proteinases fromStaphylococcus aureusandPseudomonas aeruginosa

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12 December 2020

Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line

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12 December 2020

Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor

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12 December 2020

alpha 1-Proteinase inhibitor, elastase activity, and lung disease severity in cystic fibrosis

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12 December 2020

Protease-antiprotease imbalance in the lungs of children with cystic fibrosis

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12 December 2020

Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation

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12 December 2020

Neutrophil collagenase in sputum from patients with cystic fibrosis

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12 December 2020

Advances in airway disease research. A workshop on asthma and bronchial inflammation. Monterey, California, May 19-22, 1993. Proceedings

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12 December 2020

Early pulmonary inflammation in infants with cystic fibrosis

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12 December 2020

Cystic fibrosis sputum induces a secretory response from airway gland serous cells that can be prevented by neutrophil protease inhibitors

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12 December 2020

Lower respiratory infection and inflammation in infants with newly diagnosed cystic fibrosis

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12 December 2020

Elastin and collagen degradation products in urine of patients with cystic fibrosis

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12 December 2020

Increased degranulation of eosinophil and neutrophil granulocytes in cystic fibrosis

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12 December 2020

Imbalance between 95 kDa type IV collagenase and tissue inhibitor of metalloproteinases in sputum of patients with cystic fibrosis

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12 December 2020

Pulmonary deposition and disappearance of aerosolised secretory leucocyte protease inhibitor

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12 December 2020

Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis

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12 December 2020

Inflammatory cytokines in cystic fibrosis lungs

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12 December 2020

The relationship between infection and inflammation in the early stages of lung disease from cystic fibrosis

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12 December 2020

Plasmid-liposome transfer of the alpha 1 antitrypsin gene to cystic fibrosis bronchial epithelial cells prevents elastase-induced cell detachment and cytokine release

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12 December 2020

The effects of recombinant human DNase on neutrophil elastase activity and interleukin-8 levels in the sputum of patients with cystic fibrosis

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12 December 2020

Cost-effectiveness in clinical cardiology. II. Preventive strategles and arrhythmla therapies

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12 December 2020

Effect of nebulised recombinant DNase on neutrophil elastase load in cystic fibrosis.

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12 December 2020

Disturbed myeloperoxidase-dependent activity of neutrophils in cystic fibrosis homozygotes and heterozygotes, and its correction by amiloride

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12 December 2020

Neutrophil proteinases and rhDNase therapy in cystic fibrosis

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12 December 2020

Secretory leukoprotease inhibitor: partnering alpha 1-proteinase inhibitor to combat pulmonary inflammation

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12 December 2020

The intrapulmonary half-life and safety of aerosolized alpha1-protease inhibitor in normal volunteers.

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12 December 2020

Current understanding of the inflammatory process in cystic fibrosis: onset and etiology

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12 December 2020

Positive correlation of algD transcription to lasB and lasA transcription by populations of Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis.

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12 December 2020

Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells

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12 December 2020

Alpha1-antitrypsin deficiency alleles and the Taq-I G-->A allele in cystic fibrosis lung disease.

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12 December 2020

Secretory leukoprotease inhibitor: a native antimicrobial protein presenting a new therapeutic option?

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12 December 2020

Erythromycin inhibits the production of elastase by Pseudomonas aeruginosa without affecting its proliferation in vitro

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12 December 2020

10.1177/014107689909237S05

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10472249%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10472249%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

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