Thiol-inducing and immunoregulatory effects of flavonoids in peripheral blood mononuclear cells from patients with end-stage diabetic nephropathy (Q78482755)

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scientific article published on 01 November 2002

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English	Thiol-inducing and immunoregulatory effects of flavonoids in peripheral blood mononuclear cells from patients with end-stage diabetic nephropathy	scientific article published on 01 November 2002

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12419466%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Thiol-inducing and immunoregulatory effects of flavonoids in peripheral blood mononuclear cells from patients with end-stage diabetic nephropathy (English)

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14 December 2019

diabetic nephropathy

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Jörn Dietzmann

1

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14 December 2019

Ute Thiel

2

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14 December 2019

Siegfried Ansorge

3

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14 December 2019

Klaus Hinrich Neumann

4

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14 December 2019

Michael Täger

5

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14 December 2019

publication date

1 November 2002

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14 December 2019

Free Radical Biology and Medicine

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14 December 2019

33

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14 December 2019

10

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14 December 2019

1347-1354

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14 December 2019

Cytokine overproduction in healthy first degree relatives of patients with IDDM

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Elevated glucose levels stimulate transforming growth factor-beta 1 (TGF-beta 1), suppress interleukin IL-2, IL-6 and IL-10 production and DNA synthesis in peripheral blood mononuclear cells

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Decreased secretion of Th2 cytokines precedes Up-regulated and delayed secretion of Th1 cytokines in activated peripheral blood mononuclear cells from patients with insulin-dependent diabetes mellitus.

1 reference

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Antioxidant defense system in diabetic kidney: a time course study

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Oxidative stress and enzyme activity in ambulatory renal patients undergoing continuous peritoneal dialysis

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Silibinin protects against cisplatin-induced nephrotoxicity without compromising cisplatin or ifosfamide anti-tumour activity

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Protective effects of silymarin against photocarcinogenesis in a mouse skin model

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Silibinin, a plant extract with antioxidant and membrane stabilizing properties, protects exocrine pancreas from cyclosporin A toxicity

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7 January 2021

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Presence of closely spaced protein thiols on the surface of mammalian cells.

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Redox Control of Exofacial Protein Thiols/Disulfides by Protein Disulfide Isomerase

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1 Glutathione metabolism

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Scavenging of reactive oxygen species and inhibition of arachidonic acid metabolism by silibinin in human cells

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Functions of glutathione and glutathione disulfide in immunology and immunopathology.

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Prevention of alloxan-induced diabetes mellitus in the rat by silymarin

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Restoration of the cellular thiol status of peritoneal macrophages from CAPD patients by the flavonoids silibinin and silymarin

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7 January 2021

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Evaluation of methods for measuring cellular glutathione content using flow cytometry

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7 January 2021

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Fluorescent estimation of H2O2-induced changes in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes

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Measurement of T-cell CD69 expression: a rapid and efficient means to assess mitogen- or antigen-induced proliferative capacity in normals

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Irreversible inactivation of protein kinase C by glutathione

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7 January 2021

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γ-Glutamyl transpeptidase-cellular expression in populations of normal human mononuclear cells and patients suffering from leukemias

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Novel cancer chemopreventive effects of a flavonoid antioxidant silymarin: inhibition of mRNA expression of an endogenous tumor promoter TNF alpha

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Selective inhibition of NF-kappaB activation by the flavonoid hepatoprotector silymarin in HepG2. Evidence for different activating pathways

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Identifiers

10.1016/S0891-5849(02)01043-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12419466%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12419466%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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