Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast (Q78708973)

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16 December 2019

title

Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast (English)

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16 December 2019

2

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16 December 2019

Karine Dubrana

4

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16 December 2019

Susan M. Gasser

5

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16 December 2019

author name string

Florence Hediger

1

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16 December 2019

Griet Van Houwe

3

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16 December 2019

language of work or name

English

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publication date

1 December 2002

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16 December 2019

number of pages

14

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inferred from page(s)

published in

Current Biology

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16 December 2019

volume

12

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16 December 2019

issue

24

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16 December 2019

page(s)

2076-2089

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Order and disorder in the nucleus

16 December 2019

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SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres

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Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres.

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The Dynamics of Yeast Telomeres and Silencing Proteins through the Cell Cycle

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The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae

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Limitations of silencing at native yeast telomeres

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Silencing at Drosophila telomeres: nuclear organization and chromatin structure play critical roles

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Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions

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Perinuclear localization of chromatin facilitates transcriptional silencing

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The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more.

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Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage

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7 January 2021

Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast

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7 January 2021

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression

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7 January 2021

Specific repression of the yeast silent mating locus HMR by an adjacent telomere.

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Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein

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Ku-deficient yeast strains exhibit alternative states of silencing competence

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Telomeres--unsticky ends

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DNA end-joining: from yeast to man

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Yeast Ku as a regulator of chromosomal DNA end structure

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7 January 2021

The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku.

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7 January 2021

Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

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7 January 2021

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Myosin-like proteins 1 and 2 are not required for silencing or telomere anchoring, but act in the Tel1 pathway of telomere length control.

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Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast.

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7 January 2021

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Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins.

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Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo

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Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498682%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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