Lethality in PARP-1/Ku80 double mutant mice reveals physiological synergy during early embryogenesis (Q78805217)

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16 December 2019

title

Lethality in PARP-1/Ku80 double mutant mice reveals physiological synergy during early embryogenesis (English)

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16 December 2019

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Melinda S Henrie

1

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16 December 2019

Akihiro Kurimasa

2

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16 December 2019

Sandeep Burma

3

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16 December 2019

Josiane Ménissier-de Murcia

4

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16 December 2019

Gilbert de Murcia

5

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16 December 2019

Gloria C Li

6

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16 December 2019

David J Chen

7

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16 December 2019

publication date

1 February 2003

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16 December 2019

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16 December 2019

volume

2

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16 December 2019

issue

2

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16 December 2019

page(s)

151-158

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Poly(ADP-ribose) polymerase: a molecular nick-sensor

16 December 2019

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XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

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Base excision repair is impaired in mammalian cells lacking Poly(ADP-ribose) polymerase-1.

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DNA polymerase beta -mediated long patch base excision repair. Poly(ADP-ribose)polymerase-1 stimulates strand displacement DNA synthesis.

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Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

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PARP is important for genomic stability but dispensable in apoptosis

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Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA.

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7 January 2021

Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II

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7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

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7 January 2021

DNA looping by Ku and the DNA-dependent protein kinase

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DNA end-joining: from yeast to man

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Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

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Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

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Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo

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Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis

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7 January 2021

Poly(ADP-ribose) polymerase and Ku autoantigen form a complex and synergistically bind to matrix attachment sequences

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7 January 2021

A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity.

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7 January 2021

Requirement for the Xrcc1 DNA base excision repair gene during early mouse development

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Identifiers

DOI

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16 December 2019

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