Synthesis and organotropism of 3H-dihydro derivatives of the cyanobacterial peptide hepatotoxin nodularin (Q78880708)

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17 December 2019

title

Synthesis and organotropism of 3H-dihydro derivatives of the cyanobacterial peptide hepatotoxin nodularin (English)

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17 December 2019

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Lisa Spoof

1

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17 December 2019

Svetlana Klimova

2

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17 December 2019

Andrey Mikhailov

3

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17 December 2019

John E Eriksson

4

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17 December 2019

Jussi Meriluoto

5

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17 December 2019

publication date

1 February 2003

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17 December 2019

number of pages

10

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inferred from page(s)

published in

Toxicon

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17 December 2019

volume

41

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17 December 2019

issue

2

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17 December 2019

page(s)

153-162

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A molecular basis for different interactions of marine toxins with protein phosphatase-1. Molecular models for bound motuporin, microcystins, okadaic acid, and calyculin A

17 December 2019

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Configuration assignments of the amino acid residues and the presence of N-methyldehydroalanine in toxins from the blue-green alga, Microcystis aeruginosa.

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The structure of cyanoginosin-LA, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa

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Distribution of Microcystis aeruginosa peptide toxin and interactions with hepatic microsomes in mice

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7 January 2021

Human fatalities from cyanobacteria: chemical and biological evidence for cyanotoxins

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7 January 2021

Molecular mechanisms underlying he interaction of motuporin and microcystins with type-1 and type-2A protein phosphatases

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7 January 2021

Preliminary characterization of a toxin isolated from the cyanobacterium Nodularia spumigena

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7 January 2021

Hepatocyte deformation induced by cyanobacterial toxins reflects inhibition of protein phosphatases

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7 January 2021

Pathological and biochemical characterization of microcystin-induced hepatopancreas and kidney damage in carp (Cyprinus carpio)

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7 January 2021

Microcystin-LR toxicodynamics, induced pathology, and immunohistochemical localization in livers of blue-green algae exposed rainbow trout (oncorhynchus mykiss).

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7 January 2021

Microcystin contamination in fish from the Jacarepaguá Lagoon (Rio de Janeiro, Brazil): ecological implication and human health risk

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7 January 2021

Uptake and subcellular localization of tritiated dihydro-microcystin-LR in rat liver.

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7 January 2021

Formation, characterization, and toxicity of the glutathione and cysteine conjugates of toxic heptapeptide microcystins

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7 January 2021

Detection and identification of metabolites of microcystins formed in vivo in mouse and rat livers

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7 January 2021

Berninamycin. 2. Products of acidic hydrolysis, methanolysis, and acetolysis of berninamycin A1

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7 January 2021

Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

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7 January 2021

The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1.

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7 January 2021

Synthesis, organotropism and hepatocellular uptake of two tritium-labeled epimers of dihydromicrocystin-LR, a cyanobacterial peptide toxin analog

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7 January 2021

Purification of type 1 protein (serine/threonine) phosphatases by microcystin-Sepharose affinity chromatography

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7 January 2021

Chemical characterization and toxicity of dihydro derivatives of nodularin and microcystin-LR, potent cyanobacterial cyclic peptide hepatotoxins

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7 January 2021

Two significant aspects of microcystin-LR: specific binding and liver specificity

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7 January 2021

Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR

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7 January 2021

Fatal microcystin intoxication in haemodialysis unit in Caruaru, Brazil

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7 January 2021

Characterization of chemically tritiated microcystin-LR and its distribution in mice

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7 January 2021

Lethal potency and tissue distribution of 125I-labelled toxic peptides from the blue-green alga Microcystis aeruginosa.

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7 January 2021

In vivo and in vitro binding of microcystin to protein phosphatases 1 and 2A.

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7 January 2021

Detection of nodularin in flounders and cod from the Baltic Sea

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7 January 2021

Distribution of tritiated dihydromicrocystin in swine

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7 January 2021

Toxicokinetics of tritiated dihydromicrocystin-LR in swine

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7 January 2021

Identification and estimation of microcystins in freshwater mussels

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7 January 2021

Tissue distribution and clearance of tritium-labeled dihydromicrocystin-LR epimers administered to Atlantic salmon via intraperitoneal injection

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7 January 2021

Evidence for a covalently bound form of microcystin-LR in salmon liver and Dungeness crab larvae

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7 January 2021

Immunohistochemical localization of microcystin-LR in the liver of mice: a study on the pathogenesis of microcystin-LR-induced hepatotoxicity

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7 January 2021

Inhibition of protein phosphatases by microcystins and nodularin associated with hepatotoxicity

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7 January 2021

10.1016/S0041-0101(02)00245-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12565734%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

1 reference