Effects of a monoclonal anti-alphavbeta3 integrin antibody on blood vessels - a pharmacodynamic study (Q79138723)

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19 December 2019

title

Effects of a monoclonal anti-alphavbeta3 integrin antibody on blood vessels - a pharmacodynamic study (English)

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19 December 2019

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4

George Wilding

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19 December 2019

author name string

Dahua Zhang

1

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19 December 2019

Thomas Pier

2

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19 December 2019

Douglas G McNeel

3

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19 December 2019

Andreas Friedl

5

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19 December 2019

publication date

26 September 2006

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Investigational New Drugs

19 December 2019

published in

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19 December 2019

volume

25

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19 December 2019

issue

1

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19 December 2019

page(s)

49-55

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

19 December 2019

cites work

1 reference

12 December 2020

Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis

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12 December 2020

Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3.

1 reference

12 December 2020

Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase

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12 December 2020

Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb.

1 reference

12 December 2020

1 reference

12 December 2020

Phase I trial of a monoclonal antibody specific for alphavbeta3 integrin (MEDI-522) in patients with advanced malignancies, including an assessment of effect on tumor perfusion

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12 December 2020

A reevaluation of integrins as regulators of angiogenesis

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12 December 2020

Tissue examination to monitor antiangiogenic therapy: a phase I clinical trial with endostatin

1 reference

12 December 2020

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1 reference

12 December 2020

Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor.

1 reference

12 December 2020

Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins

1 reference

12 December 2020

Pilot study of vitaxin--an angiogenesis inhibitor-in patients with advanced leiomyosarcomas

1 reference

12 December 2020

Focal adhesion kinase: the first ten years

1 reference

12 December 2020

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 reference

12 December 2020

Integrin-mediated death: an explanation of the integrin-knockout phenotype?

1 reference

12 December 2020

Focal adhesion kinase is required for blood vessel morphogenesis

1 reference

12 December 2020

Focal adhesion kinase: in command and control of cell motility

1 reference

12 December 2020

FAK integrates growth-factor and integrin signals to promote cell migration

1 reference

12 December 2020

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins

1 reference

12 December 2020

Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.

1 reference

12 December 2020

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

1 reference

12 December 2020

Application of CT in the investigation of angiogenesis in oncology

1 reference

12 December 2020

Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin alpha chains

1 reference

12 December 2020

10.1007/S10637-006-9013-8

Identifiers

DOI

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Dimensions Publication ID

19 December 2019

1013988155

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Fatcat ID

release_a3jwlniuyrbwzeqyfwzyglazze

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