Prevalence of aberrant methylation of p14ARF over p16INK4a in some human primary tumors (Q79175646)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563526%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

Prevalence of aberrant methylation of p14ARF over p16INK4a in some human primary tumors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563526%20AND%20SRC:MED&resulttype=core&format=json

Joaquin Carballido Rodriguez

20 December 2019

author

9

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20 December 2019

author name string

Gemma Dominguez

1

1 reference

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20 December 2019

Javier Silva

2

1 reference

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20 December 2019

Jose M Garcia

3

1 reference

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20 December 2019

Jose M Silva

4

1 reference

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20 December 2019

Rufo Rodriguez

5

1 reference

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20 December 2019

Concepción Muñoz

6

1 reference

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20 December 2019

Ignacio Chacón

7

1 reference

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20 December 2019

Rosario Sanchez

8

1 reference

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20 December 2019

Antonio Colás

10

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20 December 2019

Pilar España

11

1 reference

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20 December 2019

Félix Bonilla

12

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20 December 2019

language of work or name

English

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publication date

1 September 2003

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20 December 2019

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20 December 2019

volume

530

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20 December 2019

issue

1-2

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20 December 2019

page(s)

9-17

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20 December 2019

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

p14ARF links the tumour suppressors RB and p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

CpG-rich islands and the function of DNA methylation

7 January 2021

1 reference

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

DNA methylation and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Selective deletion of exon 1 beta of the p19ARF gene in metastatic melanoma cell lines.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Deletions of the INK4A gene in superficial bladder tumors. Association with recurrence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

p53 gene mutation and ink4a-arf deletion appear to be two mutually exclusive events in human glioblastoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Correlations of partial and extensive methylation at the p14(ARF) locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Alterations and hypermethylation of the p14(ARF) gene in gastric cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Analysis of genetic and epigenetic processes that influence p14ARF expression in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Number of CpG islands and genes in human and mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Concomitant expression of p16INK4a and p14ARF in primary breast cancer and analysis of inactivation mechanisms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Association of K-ras mutations with p16 methylation in human colon cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Inactivation of the p14(ARF), p15(INK4B) and p16(INK4A) genes is a frequent event in human oral squamous cell carcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

p14ARF deletion and methylation in genetic pathways to glioblastomas.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2803%2900133-7