Novel and Detrimental Effects of Lipopolysaccharide on In Vitro Generation of Immature Dendritic Cells: Involvement of Mitogen-Activated Protein Kinase p38 (Q79186748)

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scientific article published on 01 November 2003

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English	Novel and Detrimental Effects of Lipopolysaccharide on In Vitro Generation of Immature Dendritic Cells: Involvement of Mitogen-Activated Protein Kinase p38	scientific article published on 01 November 2003

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scholarly article

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20 December 2019

Novel and detrimental effects of lipopolysaccharide on in vitro generation of immature dendritic cells: involvement of mitogen-activated protein kinase p38 (English)

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20 December 2019

Novel and Detrimental Effects of Lipopolysaccharide on In Vitro Generation of Immature Dendritic Cells: Involvement of Mitogen-Activated Protein Kinase p38 (English)

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10.4049/JIMMUNOL.171.9.4792

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23 March 2024

lipopolysaccharide

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based on heuristic

inferred from title

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based on heuristic

inferred from title

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23 March 2024

author name string

Jin Xie

1

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20 December 2019

Jianfei Qian

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20 December 2019

Siqing Wang

3

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20 December 2019

Joshua Epstein

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20 December 2019

Qing Yi

6

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20 December 2019

Muta E. Freeman

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23 March 2024

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1 November 2003

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20 December 2019

Journal of Immunology

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20 December 2019

171

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20 December 2019

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20 December 2019

4792-4800

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20 December 2019

Dendritic cells and the control of immunity

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CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB

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In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

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Origin, maturation and antigen presenting function of dendritic cells.

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Dendritic cell survival and maturation are regulated by different signaling pathways.

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The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells

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A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers

9

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p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment

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IL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 Production

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Culture of bone marrow cells in GM-CSF plus high doses of lipopolysaccharide generates exclusively immature dendritic cells which induce alloantigen-specific CD4 T cell anergy in vitro

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Critical role of protein kinase C epsilon for lipopolysaccharide-induced IL-12 synthesis in monocyte-derived dendritic cells

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Identifiers

10.4049/JIMMUNOL.171.9.4792

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Europe PubMed Central

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20 December 2019

1 reference

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20 December 2019

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