Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV (Q79299443)
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scientific article published on 01 November 2006
Language | Label | Description | Also known as |
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English | Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV |
scientific article published on 01 November 2006 |
Statements
Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes (English)
Zhonghua Pei
Xiaofeng Li
Thomas W von Geldern
David J Madar
Kenton Longenecker
Hong Yong
Thomas H Lubben
Bradley A Zinker
Bradley J Backes
Andrew S Judd
Mathew Mulhern
Stephen J Ballaron
Michael A Stashko
Amanda K Mika
David W A Beno
Glenn A Reinhart
Ryan M Fryer
Lee C Preusser
Anita J Kempf-Grote
Hing L Sham
James M Trevillyan
1 November 2006