Regulation of hyperpolarization-activated HCN channels by cAMP through a gating switch in binding domain symmetry (Q79349337)

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21 December 2019

title

Regulation of hyperpolarization-activated HCN channels by cAMP through a gating switch in binding domain symmetry (English)

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21 December 2019

author name string

Chris Ulens

series ordinal

1

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21 December 2019

Steven A Siegelbaum

series ordinal

2

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21 December 2019

publication date

1 December 2003

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21 December 2019

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21 December 2019

volume

40

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21 December 2019

issue

5

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21 December 2019

page(s)

959-970

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Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

21 December 2019

cites work

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Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide

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Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

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Molecular identification of a hyperpolarization-activated channel in sea urchin sperm

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Molecular mechanism of cyclic-nucleotide-gated channel activation

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Molecular architecture of a retinal cGMP-gated channel: the arrangement of the cytoplasmic domains

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A quantitative description of membrane current and its application to conduction and excitation in nerve

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Crystal structure and mechanism of a calcium-gated potassium channel

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Crystal structure of the potassium channel KirBac1.1 in the closed state

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Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

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7 January 2021

Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers

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A family of hyperpolarization-activated mammalian cation channels

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

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Stepwise contribution of each subunit to the cooperative activation of BK channels by Ca2+.

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Hyperpolarization-activated cation currents: from molecules to physiological function

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The tetrameric structure of a glutamate receptor channel

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Single cyclic nucleotide-gated channels locked in different ligand-bound states.

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Opening mechanism of a cyclic nucleotide-gated channel based on analysis of single channels locked in each liganded state

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7 January 2021

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain

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Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin

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7 January 2021

A functioning chimera of the cyclic nucleotide-binding domain from the bovine retinal rod ion channel and the DNA-binding domain from catabolite gene-activating protein

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A state-independent interaction between ligand and a conserved arginine residue in cyclic nucleotide-gated channels reveals a functional polarity of the cyclic nucleotide binding site

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7 January 2021

Molecular mechanism for ligand discrimination of cyclic nucleotide-gated channels

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7 January 2021

Molecular mechanism of cAMP modulation of HCN pacemaker channels.

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7 January 2021

Regulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regions

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7 January 2021

Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 A resolution

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7 January 2021

Structural basis for modulation and agonist specificity of HCN pacemaker channels

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7 January 2021

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Identifiers

DOI

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21 December 2019

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