Molecular mechanisms of interleukin-10-mediated inhibition of NF-kappaB activity: a role for p50 (Q79369723)

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22 December 2019

title

Molecular mechanisms of interleukin-10-mediated inhibition of NF-kappaB activity: a role for p50 (English)

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22 December 2019

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F Driessler

1

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22 December 2019

K Venstrom

2

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22 December 2019

R Sabat

3

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22 December 2019

K Asadullah

4

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22 December 2019

A J Schottelius

5

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22 December 2019

publication date

1 January 2004

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Clinical and Experimental Immunology

22 December 2019

published in

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22 December 2019

volume

135

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22 December 2019

issue

1

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22 December 2019

page(s)

64-73

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Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse

22 December 2019

cites work

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Interleukin 10 suppresses experimental chronic, granulomatous inflammation induced by bacterial cell wall polymers

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p50 (NF-kappa B1) is upregulated in LPS tolerant P388D1 murine macrophages

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IL-10 is a key cytokine in psoriasis. Proof of principle by IL-10 therapy: a new therapeutic approach

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IL-10-mediated suppression of TNF-alpha production is independent of its ability to inhibit NF kappa B activity

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12 December 2020

Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent

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12 December 2020

Tumor necrosis factor alpha transcription in macrophages is attenuated by an autocrine factor that preferentially induces NF-kappaB p50.

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12 December 2020

Subtherapeutic corticosteroids potentiate the ability of interleukin 10 to prevent chronic inflammation in rats

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12 December 2020

Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma- induced genes by suppressing tyrosine phosphorylation of STAT1

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12 December 2020

A role for transcription factor NF-kappa B in intestinal inflammation

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12 December 2020

NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

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12 December 2020

Interleukin-10 (IL-10) selectively enhances CIS3/SOCS3 mRNA expression in human neutrophils: evidence for an IL-10-induced pathway that is independent of STAT protein activation

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12 December 2020

Immunoregulatory role of interleukin 10 in patients with inflammatory bowel disease

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Interleukin 10 prevents necrosis in murine experimental acute pancreatitis

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Transactivation domain 2 (TA2) of p65 NF-kappa B. Similarity to TA1 and phorbol ester-stimulated activity and phosphorylation in intact cells

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12 December 2020

Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysis

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12 December 2020

Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors

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12 December 2020

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

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12 December 2020

Inflammatory skin diseases, T cells, and immune surveillance

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12 December 2020

Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer

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12 December 2020

Interleukin-10 and the interleukin-10 receptor

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12 December 2020

NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction

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12 December 2020

Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophages

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12 December 2020

Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation.

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12 December 2020

Cytoplasmic retention, DNA binding and processing of the NF-kappa B p50 precursor are controlled by a small region in its C-terminus

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12 December 2020

Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit

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12 December 2020

The precursor of NF-kappa B p50 has I kappa B-like functions

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12 December 2020

Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia

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12 December 2020

The NF-kappa B precursor p105 and the proto-oncogene product Bcl-3 are I kappa B molecules and control nuclear translocation of NF-kappa B

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12 December 2020

p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction

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12 December 2020

Common structural constituents confer I kappa B activity to NF-kappa B p105 and I kappa B/MAD-3.

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12 December 2020

Interleukin-10-deficient mice develop chronic enterocolitis

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12 December 2020

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

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12 December 2020

Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding

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12 December 2020

Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms

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12 December 2020

Regulation of macrophage inflammatory protein-2 gene expression by oxidative stress in rat alveolar macrophages

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12 December 2020

Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production

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12 December 2020

Interleukin-10 prevents experimental allergic encephalomyelitis in rats.

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12 December 2020

10.1111/J.1365-2249.2004.02342.X

Identifiers

DOI

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22 December 2019

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