Removal of phosphorylation sites of gamma subunit of phosphodiesterase 6 alters rod light response (Q79397004)

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22 December 2019

title

Removal of phosphorylation sites of gamma subunit of phosphodiesterase 6 alters rod light response (English)

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22 December 2019

6

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22 December 2019

author name string

S H Tsang

1

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22 December 2019

M L Woodruff

2

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22 December 2019

Kerstin M Janisch

3

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22 December 2019

M C Cilluffo

4

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22 December 2019

D B Farber

5

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22 December 2019

publication date

30 November 2006

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22 December 2019

published in

Journal of Physiology

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22 December 2019

volume

579

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22 December 2019

issue

Pt 2

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22 December 2019

page(s)

303-312

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Two-site high-affinity interaction between inhibitory and catalytic subunits of rod cyclic GMP phosphodiesterase

22 December 2019

cites work

1 reference

12 December 2020

Domain mapping of the retinal cyclic GMP phosphodiesterase γ-subunit. Function of the domains encoded by the three exons of the γ-subunit gene

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Amplification and kinetics of the activation steps in phototransduction

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Prediction of protein secondary structure at better than 70% accuracy

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Light-dependent in vivo phosphorylation of an inhibitory subunit of cGMP-phosphodiesterase in frog rod photoreceptor outer segments

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Functional effect of phosphorylation of the photoreceptor phosphodiesterase inhibitory subunit by protein kinase C

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Phosphorylation of an inhibitory subunit of cGMP phosphodiesterase in Rana catesbeiana rod photoreceptors. II. A possible mechanism for the turnoff of cGMP phosphodiesterase without GTP hydrolysis

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Phosphorylation of an inhibitory subunit of cGMP phosphodiesterase in Rana catesbeiana rod photoreceptors. I. Characterization of the phosphorylation.

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Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase

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G-protein deactivation is rate-limiting for shut-off of the phototransduction cascade

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12 December 2020

Phosphorylation of the gamma subunit of the retinal photoreceptor cGMP phosphodiesterase by the cAMP-dependent protein kinase and its effect on the gamma subunit interaction with other proteins

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12 December 2020

Role for the target enzyme in deactivation of photoreceptor G protein in vivo

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12 December 2020

Asymmetric interaction between rod cyclic GMP phosphodiesterase gamma subunits and alphabeta subunits

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GAP-independent termination of photoreceptor light response by excess gamma subunit of the cGMP-phosphodiesterase.

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RGS expression rate-limits recovery of rod photoresponses

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Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1.

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The effector enzyme regulates the duration of G protein signaling in vertebrate photoreceptors by increasing the affinity between transducin and RGS protein

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Phosphorylation by cyclin-dependent protein kinase 5 of the regulatory subunit of retinal cGMP phosphodiesterase. I. Identification of the kinase and its role in the turnoff of phosphodiesterase in vitro

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Phosphorylation by cyclin-dependent protein kinase 5 of the regulatory subunit of retinal cGMP phosphodiesterase. II. Its role in the turnoff of phosphodiesterase in vivo

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12 December 2020

The catalytic and GAF domains of the rod cGMP phosphodiesterase (PDE6) heterodimer are regulated by distinct regions of its inhibitory gamma subunit

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12 December 2020

Regulation of photoreceptor phosphodiesterase (PDE6) by phosphorylation of its inhibitory gamma subunit re-evaluated

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12 December 2020

Measurement of cytoplasmic calcium concentration in the rods of wild-type and transducin knock-out mice

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12 December 2020

NORSp: Predictions of long regions without regular secondary structure

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Spontaneous activity of opsin apoprotein is a cause of Leber congenital amaurosis

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12 December 2020

Novel Form of Adaptation in Mouse Retinal Rods Speeds Recovery of Phototransduction

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12 December 2020

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

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12 December 2020

Spatial spread of activation and background desensitization in toad rod outer segments

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12 December 2020

Preparation and characterization of sealed bovine rod cell outer segments

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12 December 2020

Gamma-subunit of mouse retinal cyclic-GMP phosphodiesterase: cDNA and corresponding amino acid sequence

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12 December 2020

Interaction of the gamma-subunit of retinal rod outer segment phosphodiesterase with transducin. Use of synthetic peptides as functional probes

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12 December 2020

Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice

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12 December 2020

Identification of a nonsense mutation in the rod photoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse

1 reference

12 December 2020

Light-dependent delay in the falling phase of the retinal rod photoresponse

1 reference

12 December 2020

Sites of interaction between rod G-protein alpha-subunit and cGMP-phosphodiesterase gamma-subunit. Implications for the phosphodiesterase activation mechanism

1 reference

12 December 2020