Macrophages are essential for antitumour effects against weakly immunogenic murine tumours induced by class B CpG-oligodeoxynucleotides (Q79428359)

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23 December 2019

title

Macrophages are essential for antitumour effects against weakly immunogenic murine tumours induced by class B CpG-oligodeoxynucleotides (English)

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23 December 2019

author name string

Ilia N Buhtoiarov

1

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23 December 2019

Paul M Sondel

2

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23 December 2019

Jens C Eickhoff

3

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23 December 2019

Alexander L Rakhmilevich

4

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23 December 2019

publication date

8 December 2006

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23 December 2019

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23 December 2019

volume

120

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23 December 2019

page(s)

412-423

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23 December 2019

issue

3

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IFN-gamma primes RAW264 macrophages and human monocytes for enhanced oxidant production in response to CpG DNA via metabolic signaling: roles of TLR9 and myeloperoxidase trafficking

23 December 2019

cites work

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Role of macrophage phospholipase D in natural and CpG-induced antimycobacterial activity

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Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities.

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Bacterial DNA-induced NK cell IFN-gamma production is dependent on macrophage secretion of IL-12

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Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

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Cutting edge: bacterial DNA and LPS act in synergy in inducing nitric oxide production in RAW 264.7 macrophages

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Oligodeoxynucleotides containing CpG motifs can induce rejection of a neuroblastoma in mice

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Anti-CD40 antibody induces antitumor and antimetastatic effects: the role of NK cells

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Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine

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Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.

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Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

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CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitro

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CpG-oligodeoxynucleotides induce mobilization of hematopoietic progenitor cells into peripheral blood in association with mouse KC (IL-8) production

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CpG-containing oligodeoxynucleotides act through TLR9 to enhance the NK cell cytokine response to antibody-coated tumor cells

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Targeting of antigens to activated dendritic cells in vivo cures metastatic melanoma in mice

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12 December 2020

Specific siRNA downregulated TLR9 and altered cytokine expression pattern in macrophage after CpG DNA stimulation.

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Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+ T cells in patients with melanoma

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Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects

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12 December 2020

Extended sequence preferences for oligodeoxyribonucleotide activity

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12 December 2020

IFNs activate toll-like receptor gene expression in viral infections

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12 December 2020

NK- and CD8(+) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides.

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12 December 2020

Implication of macrophages in tumor rejection induced by CpG-oligodeoxynucleotides without antigen.

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12 December 2020

Immune escape of melanoma: first evidence of structural alterations in two distinct components of the MHC class I antigen processing pathway.

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12 December 2020

Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments

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12 December 2020

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12 December 2020

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12 December 2020

Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model.

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12 December 2020

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12 December 2020

Immune-mediated tumor regression induced by CpG-containing oligodeoxynucleotides

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12 December 2020

Dendritic cells are responsible for the capacity of CpG oligodeoxynucleotides to act as an adjuvant for protective vaccine immunity against Leishmania major in mice

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12 December 2020

CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma

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In vivo impact of CpG1826 oligodeoxynucleotide on CD8 T cell primary responses and survival.

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12 December 2020

CpG-A and B oligodeoxynucleotides enhance the efficacy of antibody therapy by activating different effector cell populations

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12 December 2020

Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells

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12 December 2020

Intratumor CpG-Oligodeoxynucleotide Injection Induces Protective Antitumor T Cell Immunity

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12 December 2020

In vivo CD40 ligation can induce T-cell-independent antitumor effects that involve macrophages

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12 December 2020

10.1111/J.1365-2567.2006.02517.X

Identifiers

DOI

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23 December 2019

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