Cellular communication network factor 4 (Q7953599)

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mammalian protein found in Homo sapiens

WISP1
WNT1 induced secreted protein 1
WISP1 3'UTR-associated RNA 1
Wnt-1 inducible signaling pathway protein 1
CCN4
CCN family member 4
WISP1 overlapping transcript 1 (non-protein coding)
CTC-458A3.8
WNT1-inducible-signaling pathway protein 1
Wnt-1-induced secreted protein
WNT1 inducible signaling pathway protein 1

Language	Label	Description	Also known as
English	Cellular communication network factor 4	mammalian protein found in Homo sapiens	WISP1 WNT1 induced secreted protein 1 WISP1 3'UTR-associated RNA 1 Wnt-1 inducible signaling pathway protein 1 CCN4 CCN family member 4 WISP1 overlapping transcript 1 (non-protein coding) CTC-458A3.8 WNT1-inducible-signaling pathway protein 1 Wnt-1-induced secreted protein WNT1 inducible signaling pathway protein 1

Statements

1 reference

13 November 2019

UniProt protein ID

IGFBP-related, CNN

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95388

Thrombospondin type-1 (TSP1) repeat superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95388

Growth factor receptor cysteine-rich domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95388

Glycoprotein hormone subunit beta, protein family

1 reference

based on heuristic

inferred from protein domain or family

VWFC domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cystine knot, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Insulin-like growth factor-binding protein, IGFBP family

1 reference

based on heuristic

inferred from protein domain or family

Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Thrombospondin type-1 (TSP1) repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

insulin-like growth factor binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

integrin binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

heparin binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

extracellular space

determination method

1 reference

1 January 2018

WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

extracellular matrix

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

extracellular space

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

biological process

Wnt signaling pathway

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

regulation of cell growth

determination method

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95388&geneProductId=UniProtKB:O95388

determination method

signal transduction

determination method

1 reference

8 April 2019

WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

cell-cell signaling

determination method

1 reference

8 April 2019

WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

negative regulation of cell death

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

osteoblast differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

positive regulation of smooth muscle cell migration

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

positive regulation of Wnt signaling pathway

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

osteoclast differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

negative regulation of chondrocyte differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

glucose homeostasis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

negative regulation of fat cell differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

positive regulation of osteoblast differentiation

determination method

1 reference

8 April 2019

WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

positive regulation of smooth muscle cell proliferation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

positive regulation of inflammatory response

determination method

1 reference

8 April 2019

WISP1 is a novel adipokine linked to inflammation in obesity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

bone development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

positive regulation of wound healing

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95388

determination method

Gene Atlas image

PBB GE WISP1 206796 at fs.png
732 × 530; 12 KB

0 references

Thrombospondin type-1 (TSP1) repeat

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95388

Glycoprotein hormone subunit beta

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95388

Insulin-like growth factor-binding protein, IGFBP

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95388

Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95388

Cystine knot, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95388

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95388

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000220856

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000220856

ENSP00000250160

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000250160

ENSP00000427744

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000427744

ENSP00000429185

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000429185

ENSP00000367093

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000367093

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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