Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: physiological regulator and pharmacological target for energy partitioning (Q79894781)

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scientific article published on 01 February 2007

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English	Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: physiological regulator and pharmacological target for energy partitioning	scientific article published on 01 February 2007

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17343766%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: physiological regulator and pharmacological target for energy partitioning (English)

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26 December 2019

author name string

Brian R Walker

1

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26 December 2019

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1 February 2007

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26 December 2019

Proceedings of the Nutrition Society

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26 December 2019

66

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26 December 2019

1

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26 December 2019

1-8

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26 December 2019

Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains

1 reference

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Overexpression of 11beta-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins

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7 January 2021

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Amelioration of high-fat feeding-induced insulin resistance in skeletal muscle with the antiglucocorticoid RU486.

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Inhibition of cortisol secretion by dexamethasone in relation to body fat distribution: a dose-response study

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Predicting cardiovascular risk factors from plasma cortisol measured during oral glucose tolerance tests

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Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes

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Minireview: glucocorticoids--food intake, abdominal obesity, and wealthy nations in 2004.

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Cushing's syndrome

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Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue

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Cortisol secretion in relation to body fat distribution in obese premenopausal women

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The effects of the acute administration of RU 486 on dietary fat preference in fasted lean and obese men.

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A transgenic model of visceral obesity and the metabolic syndrome

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11beta-hydroxysteroid dehydrogenase type 1 as a modulator of glucocorticoid action: from metabolism to memory

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11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice

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Effect of nutrient ingestion on total-body and splanchnic cortisol production in humans

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7 January 2021

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Minireview: hexose-6-phosphate dehydrogenase and redox control of 11{beta}-hydroxysteroid dehydrogenase type 1 activity

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7 January 2021

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RU-486 (Mifepristone) ameliorates diabetes but does not correct deficient beta-adrenergic signalling in adipocytes from mature C57BL/6J-ob/ob mice

1 reference

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7 January 2021

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Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity

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7 January 2021

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Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids.

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11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

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Local and systemic impact of transcriptional up-regulation of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue in human obesity

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Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency

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Reduced adipose glucocorticoid reactivation and increased hepatic glucocorticoid clearance as an early adaptation to high-fat feeding in Wistar rats

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7 January 2021

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Interaction between an 11betaHSD1 gene variant and birth era modifies the risk of hypertension in Pima Indians.

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7 January 2021

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Regulation of 11beta-HSD genes in human adipose tissue: influence of central obesity and weight loss

1 reference

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7 January 2021

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Portal and peripheral cortisol levels in obese humans

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Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study.

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7 January 2021

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Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice

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7 January 2021

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Stress may add bite to appetite in women: a laboratory study of stress-induced cortisol and eating behavior

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Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism

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Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice

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Local Amplification of Glucocorticoids by 11 -Hydroxysteroid Dehydrogenase Type 1 Promotes Macrophage Phagocytosis of Apoptotic Leukocytes

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7 January 2021

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Glucocorticoids as modulators in the control of feeding.

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Blockade of the Glucocorticoid Receptor with RU 486: Effects In Vitro and In Vivo on Human Adipose Tissue Lipoprotein Lipase Activity

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Influence of short-term dietary weight loss on cortisol secretion and metabolism in obese men.

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7 January 2021

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Glucocorticoid metabolism within superficial subcutaneous rather than visceral adipose tissue is associated with features of the metabolic syndrome in South African women.

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Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone.

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Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation

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7 January 2021

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Obesity and type 2 diabetes do not alter splanchnic cortisol production in humans

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7 January 2021

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Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus

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7 January 2021

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Acute in vivo regulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by insulin and intralipid infusions in humans.

1 reference

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Antidiabetic activity of passive nonsteroidal glucocorticoid receptor modulators

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Tissue-specific dysregulation of cortisol metabolism in human obesity

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7 January 2021

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11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response

1 reference

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7 January 2021

based on heuristic

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Glucocorticoids and 11beta-hydroxysteroid dehydrogenase in adipose tissue

1 reference

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7 January 2021

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Genetic variation in 11beta-hydroxysteroid dehydrogenase type 1 predicts adrenal hyperandrogenism among lean women with polycystic ovary syndrome.

1 reference

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7 January 2021

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7 January 2021

based on heuristic

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Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Hexose-6-phosphate dehydrogenase knock-out mice lack 11 beta-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans

1 reference

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7 January 2021

based on heuristic

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11 beta-hydroxysteroid dehydrogenase type 1 induction in the arcuate nucleus by high-fat feeding: A novel constraint to hyperphagia?

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

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Splanchnic cortisol production occurs in humans: evidence for conversion of cortisone to cortisol via the 11-beta hydroxysteroid dehydrogenase (11beta-hsd) type 1 pathway

1 reference

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7 January 2021

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Type 1 11beta -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets

1 reference

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7 January 2021

based on heuristic

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Effects of RU 486 on energy expenditure and meal tolerance in normal men

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Glucocorticoid receptor messenger ribonucleic acid in different regions of human adipose tissue

1 reference

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7 January 2021

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inferred from DOI database lookup

Role of leptin in the neuroendocrine response to fasting

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Intra-vascular glucocorticoid metabolism as a modulator of vascular structure and function

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Co-administration of etomoxir and RU-486 mitigates insulin resistance in hepatic and muscular tissues of STZ-induced diabetic rats

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A novel promoter for the 11beta-hydroxysteroid dehydrogenase type 1 gene is active in lung and is C/EBPalpha independent.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Down-regulation of adipose 11beta-hydroxysteroid dehydrogenase type 1 by high-fat feeding in mice: a potential adaptive mechanism counteracting metabolic disease

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Subcutaneous adipose 11 beta-hydroxysteroid dehydrogenase type 1 activity and messenger ribonucleic acid levels are associated with adiposity and insulinemia in Pima Indians and Caucasians

1 reference

https://api.crossref.org/works/10.1017%2FS002966510700523X

7 January 2021

based on heuristic

inferred from DOI database lookup

11beta-Hydroxysteroid dehydrogenase Type 1: genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Independent effects of obesity and cortisol in predicting cardiovascular risk factors in men and women.

1 reference

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7 January 2021

based on heuristic

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Identifiers

10.1017/S002966510700523X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17343766%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17343766%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

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