Sustained AAV-mediated dystrophin expression in a canine model of Duchenne muscular dystrophy with a brief course of immunosuppression (Q80141652)

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29 December 2019

title

Sustained AAV-mediated dystrophin expression in a canine model of Duchenne muscular dystrophy with a brief course of immunosuppression (English)

1 reference

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Duchenne muscular dystrophy

29 December 2019

main subject

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5

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8

Rainer Storb

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1

Zejing Wang

1 reference

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author name string

Christian S Kuhr

2

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29 December 2019

James M Allen

3

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29 December 2019

Michael Blankinship

4

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29 December 2019

Jeffrey S Chamberlain

6

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Stephen J Tapscott

7

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29 December 2019

publication date

10 April 2007

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29 December 2019

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29 December 2019

volume

15

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issue

6

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page(s)

1160-1166

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Dystrophin and mutations: one gene, several proteins, multiple phenotypes

29 December 2019

cites work

1 reference

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7 January 2021

Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

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Efficient transduction of skeletal muscle using vectors based on adeno-associated virus serotype 6.

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Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.

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Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart

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Recombinant adeno-associated viral (rAAV) vectors as therapeutic tools for Duchenne muscular dystrophy (DMD).

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7 January 2021

Gene therapy strategies for Duchenne muscular dystrophy utilizing recombinant adeno-associated virus vectors.

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Very mild muscular dystrophy associated with the deletion of 46% of dystrophin

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Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice

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7 January 2021

Modular flexibility of dystrophin: implications for gene therapy of Duchenne muscular dystrophy

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7 January 2021

Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain

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7 January 2021

Viral vectors for gene transfer of micro-, mini-, or full-length dystrophin

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rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.

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7 January 2021

Systemic delivery of genes to striated muscles using adeno-associated viral vectors.

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7 January 2021

Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury.

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7 January 2021

Microdystrophin gene therapy of cardiomyopathy restores dystrophin-glycoprotein complex and improves sarcolemma integrity in the mdx mouse heart.

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7 January 2021

C-terminal-truncated microdystrophin recruits dystrobrevin and syntrophin to the dystrophin-associated glycoprotein complex and reduces muscular dystrophy in symptomatic utrophin/dystrophin double-knockout mice

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7 January 2021

Immunity to adeno-associated virus-mediated gene transfer in a random-bred canine model of Duchenne muscular dystrophy

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7 January 2021

Cyclosporin A, a powerful immunosuppressant in vivo and in vitro in the dog, fails to induce tolerance

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7 January 2021

Mycophenolate mofetil and its mechanisms of action

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7 January 2021

Immunosuppressive agents in solid organ transplantation: Mechanisms of action and therapeutic efficacy.

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Crossing the bridge: large animal models in translational transplantation research

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7 January 2021

An error in dystrophin mRNA processing in golden retriever muscular dystrophy, an animal homologue of Duchenne muscular dystrophy

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7 January 2021

Muscle-directed gene transfer and transient immune suppression result in sustained partial correction of canine hemophilia B caused by a null mutation

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7 January 2021

Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1.

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7 January 2021

Dissection of temporal gene expression signatures of affected and spared muscle groups in dystrophin-deficient (mdx) mice

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7 January 2021

Persistent over-expression of specific CC class chemokines correlates with macrophage and T-cell recruitment in mdx skeletal muscle

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7 January 2021

Damage and inflammation in muscular dystrophy: potential implications and relationships with autoimmune myositis

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7 January 2021

Muscle-derived positive and negative regulators of the immune response

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7 January 2021

Immune evasion by muscle-specific gene expression in dystrophic muscle

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7 January 2021

Adeno-associated virus vector-mediated gene transfer into dystrophin-deficient skeletal muscles evokes enhanced immune response against the transgene product

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7 January 2021

Cyclophosphamide and antithymocyte globulin as a conditioning regimen for allogeneic marrow transplantation in patients with aplastic anaemia: a long-term follow-up

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7 January 2021

What role is there for antithymocyte globulin in allogeneic nonmyeloablative canine hematopoietic cell transplantation?

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7 January 2021

Origins and early descriptions of "Duchenne muscular dystrophy".

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7 January 2021

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

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7 January 2021

Identification of mouse AAV capsid-specific CD8+ T cell epitopes

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7 January 2021

Determination of specific CD4 and CD8 T cell epitopes after AAV2- and AAV8-hF.IX gene therapy

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7 January 2021

Biology of AAV serotype vectors in liver-directed gene transfer to nonhuman primates.

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7 January 2021

Hematopoietic stem cell transplantation does not restore dystrophin expression in Duchenne muscular dystrophy dogs

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7 January 2021

Progress in adeno-associated virus type 2 vector production: promises and prospects for clinical use.

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7 January 2021

Forced expression of dystrophin deletion constructs reveals structure-function correlations.

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7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300161

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17426713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference