Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas (Q80238304)

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30 December 2019

title

Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas (English)

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30 December 2019

1

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30 December 2019

Cécile Godard

3

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30 December 2019

author name string

Benhamouche S

2

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30 December 2019

Boyault S

4

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30 December 2019

Grimber G

5

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30 December 2019

Balabaud C

6

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30 December 2019

Cunha AS

7

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30 December 2019

Bioulac-Sage P

8

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30 December 2019

Perret C

9

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30 December 2019

publication date

11 September 2006

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30 December 2019

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30 December 2019

volume

26

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30 December 2019

page(s)

774-780

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30 December 2019

issue

5

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209824

30 December 2019

exact match

0 references

cites work

Hepatocellular carcinoma: diagnosis and treatment

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7 January 2021

New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism

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Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas

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Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

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7 January 2021

Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway

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Identification of c-MYC as a target of the APC pathway

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Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis

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7 January 2021

Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection

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7 January 2021

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

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Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis

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Genetics of hepatocellular tumors.

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Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity.

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7 January 2021

Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation

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7 January 2021

Identification of the leukocyte cell-derived chemotaxin 2 as a direct target gene of beta-catenin in the liver.

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7 January 2021

Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation

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7 January 2021

The links between axin and carcinogenesis

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7 January 2021

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

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7 January 2021

Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

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7 January 2021

Close correlation between beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas.

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7 January 2021

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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7 January 2021

Overexpression of orphan G-protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with beta-catenin mutations

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7 January 2021

Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase

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7 January 2021

Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling

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7 January 2021