Efficacy and Safety of the Platelet-Activating Factor Receptor Antagonist BN 52021 (Ginkgolide B) in Patients with Severe Sepsis : A Randomised, Double-Blind, Placebo-Controlled, Multicentre Trial (Q80363792)

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scientific article published on 01 January 2004

Language	Label	Description	Also known as
English	Efficacy and Safety of the Platelet-Activating Factor Receptor Antagonist BN 52021 (Ginkgolide B) in Patients with Severe Sepsis : A Randomised, Double-Blind, Placebo-Controlled, Multicentre Trial	scientific article published on 01 January 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Efficacy and Safety of the Platelet-Activating Factor Receptor Antagonist BN 52021 (Ginkgolide B) in Patients with Severe Sepsis : A Randomised, Double-Blind, Placebo-Controlled, Multicentre Trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

based on heuristic

inferred from title

multicenter clinical trial

1 reference

based on heuristic

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based on heuristic

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author name string

D M Albrecht

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

K van Ackern

2

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Europe PubMed Central

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30 December 2019

H-J Bender

3

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30 December 2019

H Hof

4

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Europe PubMed Central

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30 December 2019

W Kox

5

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30 December 2019

N Victor

6

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30 December 2019

P Funk

7

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30 December 2019

M Kieser

8

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30 December 2019

S Köhler

9

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30 December 2019

D Krausch

10

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30 December 2019

I Marzi

11

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30 December 2019

T Menges

12

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30 December 2019

H Schmidt

13

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30 December 2019

publication date

1 January 2004

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30 December 2019

Clinical Drug Investigation

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30 December 2019

24

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30 December 2019

3

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30 December 2019

137-147

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Europe PubMed Central

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30 December 2019

Intensive Care Society's APACHE II study in Britain and Ireland--I: Variations in case mix of adult admissions to general intensive care units and impact on outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

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Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treating patients with severe sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravascular release of platelet activating factor in children with sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Multiple Testing Procedure for Clinical Trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An expanded definition of the adult respiratory distress syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma degradation of platelet-activating factor in severely ill patients with clinical sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Occupancy of platelet receptors for platelet-activating factor in patients with septicemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

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Platelet activating factor receptor antagonist improves survival and attenuates eicosanoid release in severe endotoxemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

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The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perspectives in platelet-activating factor research

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

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4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene and outcome of meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between platelet activating factor and eicosanoids during endotoxic shock in anaesthetized pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective study of aetiology and outcome of adult lower-respiratory-tract infections in the community

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A PAF receptor antagonist, BN 52021, attenuates thromboxane release and improves survival in lethal canine endotoxemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-activating factor receptor antagonist BN 52021 in the treatment of severe sepsis: a randomized, double-blind, placebo-controlled, multicenter clinical trial. BN 52021 Sepsis Study Group.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased organ failure in patients with severe SIRS and septic shock treated with the platelet-activating factor antagonist TCV-309: a prospective, multicenter, double-blind, randomized phase II trial. TCV-309 Septic Shock Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of PAF-acether and blood volume changes in gram-negative sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

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Test statistics and sample size formulae for comparative binomial trials with null hypothesis of non-zero risk difference or non-unity relative risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Outcomes research exemplified by infection]

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet activating factor and its role in trauma, shock, and sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet activating factor is one of the mediators involved in endotoxic shock in pigs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic options directed against platelet activating factor, eicosanoids and bradykinin in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

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Treatment with the platelet-activating factor antagonist TCV-309 in patients with severe systemic inflammatory response syndrome: a prospective, multi-center, double-blind, randomized phase II trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variation in plasminogen-activator-inhibitor-1 gene and risk of meningococcal septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Confirmatory platelet-activating factor receptor antagonist trial in patients with severe gram-negative bacterial sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. BN 52021 Sepsis Investigator Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simplified acute physiology score for ICU patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APACHE II: a severity of disease classification system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00044011-200424030-00002

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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