Engineering predictability and protraction in a basal insulin analogue: the pharmacology of insulin detemir (Q80442179)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306834%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

review article

1 reference

title

Engineering predictability and protraction in a basal insulin analogue: the pharmacology of insulin detemir (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306834%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

1 reference

P Kurtzhals

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306834%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

publication date

1 September 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306834%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

volume

28 Suppl 2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306834%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

page(s)

S23-8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306834%20AND%20SRC:MED&resulttype=core&format=json

The reality of glycaemic control in insulin treated diabetes: defining the clinical challenges

31 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Novel forms of insulin delivery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Role of zinc in insulin biosynthesis. Some possible zinc-insulin interactions in the pancreatic B-cell

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Basal and 24-h C-peptide and insulin secretion rate in normal man

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Subcutaneous Insulin Absorption Explained by Insulin's Physicochemical Properties: Evidence From Absorption Studies of Soluble Human Insulin and Insulin Analogues in Humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Diffusion and polymerization determines the insulin absorption from subcutaneous tissue in diabetic patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Monomeric insulins obtained by protein engineering and their medical implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Absorption of isophane (NPH) insulin and its clinical implications.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Variability of insulin absorption and insulin action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Limitations to subcutaneous insulin administration in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Monomeric insulins and their experimental and clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Insulin analogs with improved pharmacokinetic profiles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Physiological insulin replacement in type 1 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Inadequate suspension of neutral protamine Hagendorn (NPH) insulin in pens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Insulins today and beyond

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Insulin analogues and other developments in insulin therapy for diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Pharmacokinetics of 125I-labeled insulin glargine (HOE 901) in healthy men: comparison with NPH insulin and the influence of different subcutaneous injection sites.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

New insulins in the treatment of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Soluble, prolonged-acting insulin derivatives. I. Degree of protraction and crystallizability of insulins substituted in the termini of the B-chain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Soluble, prolonged-acting insulin derivatives. II. Degree of protraction and crystallizability of insulins substituted in positions A17, B8, B13, B27 and B30

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Action profile of cobalt(III)-insulin. A novel principle of protraction of potential use for basal insulin delivery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

The cobalt(III)-insulin hexamer is a prolonged-acting insulin prodrug

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Albumin binding of insulins acylated with fatty acids: characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

The Mechanism of Protraction of Insulin Detemir, a Long-Acting, Acylated Analog of Human Insulin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Crystal structure of a prolonged-acting insulin with albumin-binding properties

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Mechanism of protracted metabolic effects of fatty acid acylated insulin, NN304, in dogs: retention of NN304 by albumin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Mode of transcapillary transport of insulin and insulin analog NN304 in dog hindlimb: evidence for passive diffusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Albumin binding of acylated insulin (NN304) does not deter action to stimulate glucose uptake

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Insulin detemir: improving the predictability of glycaemic control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Effect of fatty acids and selected drugs on the albumin binding of a long-acting, acylated insulin analogue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Pharmacokinetic and pharmacodynamic properties of long-acting insulin analogue NN304 in comparison to NPH insulin in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

A comparison of postprandial and preprandial administration of insulin aspart in children and adolescents with type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802746

7 January 2021

Identifiers

DOI

10.1038/SJ.IJO.0802746

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306834%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference