Phospholamban ablation by RNA interference increases Ca2+ uptake into rat cardiac myocyte sarcoplasmic reticulum (Q80532852)

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1 January 2020

title

Phospholamban ablation by RNA interference increases Ca2+ uptake into rat cardiac myocyte sarcoplasmic reticulum (English)

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1 January 2020

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Atai Watanabe

1

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1 January 2020

Masashi Arai

2

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1 January 2020

Miki Yamazaki

3

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1 January 2020

Norimichi Koitabashi

4

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1 January 2020

Frank Wuytack

5

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1 January 2020

Masahiko Kurabayashi

6

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publication date

1 September 2004

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Journal of Molecular and Cellular Cardiology

1 January 2020

published in

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volume

37

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1 January 2020

page(s)

691-698

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1 January 2020

issue

3

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Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure

1 January 2020

cites work

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Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure

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Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts

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Enhanced myocardial contractility and increased Ca2+ transport function in transgenic hearts expressing the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase

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Phospholamban: a prominent regulator of myocardial contractility

7 January 2021

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Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation

7 January 2021

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Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy

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Targeting phospholamban by gene transfer in human heart failure

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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Comparison of the Suppressive Effects of Antisense Oligonucleotides and siRNAs Directed Against the Same Targets in Mammalian Cells

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Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system

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Cloning and characterization of the gene encoding rabbit cardiac calsequestrin

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Expression of endoplasmic-reticulum Ca2(+)-pump isoforms and of phospholamban in pig smooth-muscle tissues

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Regulation of Ca2+ transport by cyclic 3',5'-AMP-dependent and calcium-calmodulin-dependent phosphorylation of cardiac sarcoplasmic reticulum

7 January 2021

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Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium

7 January 2021

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Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium

7 January 2021

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Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure

7 January 2021

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Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery

7 January 2021

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Impaired cardiac performance in heterozygous mice with a null mutation in the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 (SERCA2) gene

7 January 2021

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Phospholamban gene dosage effects in the mammalian heart

7 January 2021

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Rescue of contractile parameters and myocyte hypertrophy in calsequestrin overexpressing myocardium by phospholamban ablation

7 January 2021

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Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy

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U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.

7 January 2021

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Effective expression of small interfering RNA in human cells

7 January 2021

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Ultrasound-targeted microbubble destruction can repeatedly direct highly specific plasmid expression to the heart

7 January 2021

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New efficient catheter-based system for myocardial gene delivery

7 January 2021

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7 January 2021

Identifiers

DOI

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1 January 2020

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