GAD autoantibodies and epitope reactivities persist after diagnosis in latent autoimmune diabetes in adults but do not predict disease progression: UKPDS 77 (Q80685980)

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scientific article published on 27 July 2007

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English	GAD autoantibodies and epitope reactivities persist after diagnosis in latent autoimmune diabetes in adults but do not predict disease progression: UKPDS 77	scientific article published on 27 July 2007

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2 January 2020

GAD autoantibodies and epitope reactivities persist after diagnosis in latent autoimmune diabetes in adults but do not predict disease progression: UKPDS 77 (English)

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2 January 2020

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2 January 2020

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2 January 2020

Jonathan Cummings Levy

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2 January 2020

Polly J. Bingley

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P J Bingley

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2 January 2020

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M Desai

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2 January 2020

C A Cull

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2 January 2020

V A Horton

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2 January 2020

M R Christie

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2 January 2020

I R Mackay

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2 January 2020

P Zimmet

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2 January 2020

A Clark

12

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2 January 2020

publication date

27 July 2007

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2 January 2020

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2 January 2020

50

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2 January 2020

10

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2 January 2020

2052-2060

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2 January 2020

Unique epitopes of glutamic acid decarboxylase autoantibodies in slowly progressive type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantibodies associated with Type I diabetes mellitus persist after diagnosis in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantibodies to glutamic acid decarboxylase in diabetic patients from a multi-ethnic Australian community: the Fremantle Diabetes Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maturation of the humoral autoimmune response to epitopes of GAD in preclinical childhood type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An association analysis of the HLA gene region in latent autoimmune diabetes in adults.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Declassifying diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UK Prospective Diabetes Study (UKPDS). VIII. Study design, progress and performance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic heterogeneity of autoimmune diabetes: age of presentation in adults is influenced by HLA DRB1 and DQB1 genotypes (UKPDS 43). UK Prospective Diabetes Study (UKPDS) Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet autoantibodies in clinically diagnosed type 2 diabetes: prevalence and relationship with metabolic control (UKPDS 70).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correct homeostasis model assessment (HOMA) evaluation uses the computer program

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantibody recognition of COOH-terminal epitopes of GAD65 marks the risk for insulin requirement in adult-onset diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistence of serum antibodies to 64,000-Mr islet cell protein after onset of type I diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross reactivity between IA-2 and phogrin/IA-2beta in binding of autoantibodies in IDDM

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant Fabs of human monoclonal antibodies specific to the middle epitope of GAD65 inhibit type 1 diabetes-specific GAD65Abs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet cell antibodies at diagnosis, but not leanness, relate to a better cardiovascular risk factor profile 5 years after diagnosis of NIDDM

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UK Prospective Diabetes Study (UKPDS). XI: Biochemical risk factors in type 2 diabetic patients at diagnosis compared with age-matched normal subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell insulitis found in anti-GAD65+ diabetes with residual beta-cell function. A case report

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Humoral autoimmune responses to glutamic acid decarboxylase have similar target epitopes and subclass that show titer-dependent disease association

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 12-year prospective study of the relationship between islet antibodies and beta-cell function at and after the diagnosis in patients with adult-onset diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stable GAD65 autoantibody epitope patterns in type 1 diabetes children five years after onset

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IA-2 antibody prevalence and risk assessment of early insulin requirement in subjects presenting with type 2 diabetes (UKPDS 71).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluctuations in GAD65 antibodies after clinical diagnosis of IDDM in young children

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic beta cells in insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GAD antibodies in probands and their relatives in a cohort clinically selected for Type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Variable Number of Tandem Repeats Upstream of the Insulin Gene Is a Susceptibility Locus for Latent Autoimmune Diabetes in Adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similar genetic features and different islet cell autoantibody pattern of latent autoimmune diabetes in adults (LADA) compared with adult-onset type 1 diabetes with rapid progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comment on: Gale EAM (2005) Latent autoimmune diabetes in adults: a guide for the perplexed. Diabetologia 48:2195-2199

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Titre and combination of ICA and autoantibodies to glutamic acid decarboxylase discriminate two clinically distinct types of latent autoimmune diabetes in adults (LADA).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes-associated autoantibodies in relation to clinical characteristics and natural course in children with newly diagnosed type 1 diabetes. The Childhood Diabetes In Finland Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/17657474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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