A Kinetic Model for Simultaneous Fit of Clozapine and Norclozapine Concentrations in Chronic Schizophrenic Patients during Long-Term Treatment (Q80967258)

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scientific article published on 01 January 1998

Language	Label	Description	Also known as
English	A Kinetic Model for Simultaneous Fit of Clozapine and Norclozapine Concentrations in Chronic Schizophrenic Patients during Long-Term Treatment	scientific article published on 01 January 1998

Statements

scholarly article

1 reference

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4 January 2020

A Kinetic Model for Simultaneous Fit of Clozapine and Norclozapine Concentrations in Chronic Schizophrenic Patients during Long-Term Treatment (English)

1 reference

Europe PubMed Central

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4 January 2020

1 reference

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author name string

C Guitton

1

1 reference

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4 January 2020

J M Kinowski

2

1 reference

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4 January 2020

R Gomeni

3

1 reference

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4 January 2020

F Bressolle

4

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4 January 2020

publication date

1 January 1998

1 reference

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4 January 2020

Clinical Drug Investigation

1 reference

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4 January 2020

16

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4 January 2020

1

1 reference

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4 January 2020

35-43

1 reference

Europe PubMed Central

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4 January 2020

Single- vs multiple-dose pharmacokinetics of clozapine in psychiatric patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Update on the clinical efficacy and side effects of clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

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Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

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D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

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Population pharmacokinetics of clozapine evaluated with the nonparametric maximum likelihood method

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antagonism by neuroleptics of serotonin 5-HT1A and 5-HT2 receptors of normal human brain in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of phenytoin on plasma clozapine concentrations in two patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated levels of clozapine in serum after addition of fluvoxamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine. A novel antipsychotic agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple-dose pharmacokinetics of moxisylyte after oral administration to healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leponex--associated granulocytopenia: a review of the situation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antipsychotic clozapine is metabolized by the polymorphic human microsomal and recombinant cytochrome P450 2D6

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of clozapine in chronic schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-related plasma levels of clozapine: influence of smoking behaviour, sex and age

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluvoxamine Inhibition and Carbamazepine Induction of the Metabolism of Clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple-dose pharmacokinetics of ceftibuten after oral administration to healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine and N-desmethylclozapine are potent 5-HT1C receptor antagonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antipsychotic efficacy in relation to plasma levels of clozapine (author's transl)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple-dose pharmacokinetics of pefloxacin in patients with hepatocellular deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor and mental side effects of clozapine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A case report of cimetidine-induced clozapine toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine--pharmacokinetic investigations and biochemical effects in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine: guidelines for clinical management

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical evaluation and plasma clozapine concentrations in Chinese patients with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of clozapine and desmethylclozapine in schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictors of response to clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine and norclozapine plasma concentrations and clinical response of treatment-refractory schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of neuroleptics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple-dose pharmacokinetics of clozapine in patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma clozapine concentrations as a predictor of clinical response: a follow-up study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of typical and atypical antipsychotics to 5-HT1C and 5-HT2 sites: clozapine potently interacts with 5-HT1C sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of clozapine and its major metabolites in human plasma and red blood cells by high-performance liquid chromatography with ultraviolet absorbance detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple-dose pharmacokinetics of amikacin and ceftazidime in critically ill patients with septic multiple-organ failure during intermittent hemofiltration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum concentrations of clozapine and its major metabolites: effects of cotreatment with fluoxetine or valproate

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships between effects and plasma levels of clozapine (author's transl)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interactions involving clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of clozapine and its N-demethylated metabolite in plasma by use of gas chromatography-mass spectrometry with single ion detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictors of clozapine response in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma clozapine concentrations predict clinical response in treatment-resistant schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine and metabolites: concentrations in serum and clinical findings during treatment of chronically psychotic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of clozapine in man: lack of association with debrisoquine and S-mephenytoin hydroxylation polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/18370516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00044011-199816010-00005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18370516%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18370516%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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