Fat storage in pancreas and in insulin-sensitive tissues in pathogenesis of type 2 diabetes (Q81127038)

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6 January 2020

review article

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title

Fat storage in pancreas and in insulin-sensitive tissues in pathogenesis of type 2 diabetes (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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F Assimacopoulos-Jeannet

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

publication date

1 December 2004

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

28 Suppl 4

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6 January 2020

page(s)

S53-7

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What if Minkowski had been ageusic? An alternative angle on diabetes

6 January 2020

cites work

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7 January 2021

Nutritional effects of fat on carbohydrate metabolism

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7 January 2021

The stimulus-secretion coupling of glucose-induced insulin release: fuel metabolism in islets deprived of exogenous nutrient

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7 January 2021

Hole of plasma free fatty acids in the control of insulin secretion in man

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7 January 2021

Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans

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7 January 2021

Stimulation of insulin secretion by infusion of free fatty acids

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7 January 2021

Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects.

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7 January 2021

The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation

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7 January 2021

Signal transduction mechanisms in nutrient-induced insulin secretion

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7 January 2021

A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion

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7 January 2021

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

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7 January 2021

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

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7 January 2021

Beta-cell hypersensitivity to glucose following 24-h exposure of rat islets to fatty acids

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7 January 2021

Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1.

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7 January 2021

Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Glucose-induced preproinsulin gene expression is inhibited by the free fatty acid palmitate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats

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https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells

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https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Chronic effect of fatty acids on insulin release is not through the alteration of glucose metabolism in a pancreatic beta-cell line (beta HC9).

1 reference

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7 January 2021

Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function

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https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death

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7 January 2021

Mechanisms decreasing glucose oxidation in diabetes and starvation: role of lipid fuels and hormones.

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7 January 2021

Cellular mechanisms of insulin resistance

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7 January 2021

Muscle triglyceride and insulin resistance

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https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

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https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice

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https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

A new antidiabetic agent, BRL 49653, reduces lipid availability and improves insulin action and glucoregulation in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Increased efficiency of fatty acid uptake contributes to lipid accumulation in skeletal muscle of high fat-fed insulin-resistant rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

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7 January 2021

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

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7 January 2021

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Acyl-CoA inhibition of hexokinase in rat and human skeletal muscle is a potential mechanism of lipid-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857

7 January 2021

Identifiers

DOI

10.1038/SJ.IJO.0802857

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference