CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells (Q81157149)

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6 January 2020

title

CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells (English)

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6 January 2020

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1

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6 January 2020

Philippe Saas

4

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5

Jeffrey A Bluestone

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6 January 2020

author name string

Pin Zhang

2

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6 January 2020

Yongzhong Liu

3

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6 January 2020

Wanjun Chen

6

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publication date

27 April 2008

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6 January 2020

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6 January 2020

volume

14

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issue

5

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page(s)

528-535

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https://scigraph.springernature.com/pub.10.1038/nm1749

6 January 2020

exact match

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cites work

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7 January 2021

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Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy

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TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

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Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25- LAP+ T cells.

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7 January 2021

TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu

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7 January 2021

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

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T cells are just dying to accept grafts

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Anti-tumor necrosis factor modulates anti-CD3-triggered T cell cytokine gene expression in vivo

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7 January 2021

Intravenous apoptotic spleen cell infusion induces a TGF-beta-dependent regulatory T-cell expansion

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7 January 2021

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

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7 January 2021

Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes

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Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells

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Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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7 January 2021

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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7 January 2021

Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter

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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

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T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis

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7 January 2021

Transforming growth factor-beta induces development of the T(H)17 lineage

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7 January 2021

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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7 January 2021

Treatment with nonmitogenic anti-CD3 monoclonal antibody induces CD4+ T cell unresponsiveness and functional reversal of established experimental autoimmune encephalomyelitis

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7 January 2021

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

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7 January 2021

TGFbeta protein processing and activity through TCR triggering of primary CD8+ T regulatory cells

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7 January 2021

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production

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7 January 2021

Distribution and modulation of the cellular receptor for transforming growth factor-beta

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7 January 2021

IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors

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7 January 2021

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

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7 January 2021

Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

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7 January 2021

Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.

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7 January 2021

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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7 January 2021

Requirement of CD28 signaling in homeostasis/survival of TGF-beta converted CD4+CD25+ Tregs from thymic CD4+CD25- single positive T cells

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7 January 2021

A single-platform approach using flow cytometry and microbeads to evaluate immune reconstitution in mice after bone marrow transplantation

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7 January 2021

Identifiers

DOI

10.1038/NM1749

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18438416%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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