DPYD*5 gene mutation contributes to the reduced DPYD enzyme activity and chemotherapeutic toxicity of 5-FU: results from genotyping study on 75 gastric carcinoma and colon carcinoma patients (Q81234951)

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scientific article published on 01 January 2007

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English	DPYD*5 gene mutation contributes to the reduced DPYD enzyme activity and chemotherapeutic toxicity of 5-FU: results from genotyping study on 75 gastric carcinoma and colon carcinoma patients	scientific article published on 01 January 2007

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

DPYD*5 gene mutation contributes to the reduced DPYD enzyme activity and chemotherapeutic toxicity of 5-FU: results from genotyping study on 75 gastric carcinoma and colon carcinoma patients (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

based on heuristic

inferred from title

colon carcinoma

1 reference

based on heuristic

inferred from title

author name string

Hong Zhang

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

You-ming Li

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Hao Zhang

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Xi Jin

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

publication date

1 January 2007

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Medical Oncology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

24

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

251-258

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17848752%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Pharmacogenetics in cancer treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human polymorphism in drug metabolism: mutation in the dihydropyrimidine dehydrogenase gene results in exon skipping and thymine uracilurea.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparative analysis of translated dihydropyrimidine dehydrogenase cDNA; conservation of functional domains and relevance to genetic polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nomenclature for human DPYD alleles

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene: identification of a new polymorphism related with effects of 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenomics and stomach cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple and rapid high-performance liquid chromatographic (HPLC) method for 5-fluorouracil (5-FU) assay in plasma and possible detection of patients with impaired dihydropyrimidine dehydrogenase (DPD) activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetic and clinical aspects of dihydropyrimidine dehydrogenase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of pyrosequencing to detect clinically relevant polymorphisms in dihydropyrimidine dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydropyrimidine dehydrogenase pharmacogenetics in the Taiwanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variation as a guide to drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer pharmacogenomics: powerful tools in cancer chemotherapy and drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)- related toxicity compared with controls.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased risk of grade IV neutropenia after administration of 5-fluorouracil due to a dihydropyrimidine dehydrogenase deficiency: high prevalence of the IVS14+1g>a mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxic death-case after capecitabine + oxaliplatin (XELOX) administration: probable implication of dihydropyrimidine deshydrogenase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the human dihydropyrimidine dehydrogenase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple organ failure due to 5-fluorouracil chemotherapy in a patient with a rare dihydropyrimidine dehydrogenase gene variant

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High prevalence of the IVS14 + 1G>A mutation in the dihydropyrimidine dehydrogenase gene of patients with severe 5-fluorouracil-associated toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of dihydropyrimidine dehydrogenase (DPD) deficiency in patients exhibiting toxicity following treatment with 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/17848752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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