Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1 (Q81308372)

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7 January 2020

title

Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1 (English)

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7 January 2020

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8

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author name string

B H Huang

1

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M Laban

2

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C H-W Leung

3

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L Lee

4

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C K Lee

5

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M Salto-Tellez

6

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G C Raju

7

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publication date

1 April 2005

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Cell Death & Differentiation

7 January 2020

published in

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volume

12

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7 January 2020

page(s)

395-404

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7 January 2020

issue

4

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401567

7 January 2020

exact match

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p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription

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Yeast TAF(II)145 required for transcription of G1/S cyclin genes and regulated by the cellular growth state

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Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation

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Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation

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The ts13 mutation in the TAF(II)250 subunit (CCG1) of TFIID directly affects transcription of D-type cyclin genes in cells arrested in G1 at the nonpermissive temperature

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Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

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Role of the histone deacetylase complex in acute promyelocytic leukaemia

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7 January 2021

Deacetylation of p53 modulates its effect on cell growth and apoptosis

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7 January 2021

Histone deacetylases specifically down-regulate p53-dependent gene activation

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

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Retinoblastoma protein recruits histone deacetylase to repress transcription

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Retinoblastoma protein represses transcription by recruiting a histone deacetylase

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Rb interacts with histone deacetylase to repress transcription

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BRCA1 interacts with components of the histone deacetylase complex

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Histone deacetylases (HDACs): characterization of the classical HDAC family

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Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

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A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

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Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

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Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

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Sin meets NuRD and other tails of repression.

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Histone deacetylase activity is required for full transcriptional repression by mSin3A

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NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities

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Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

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Reliability of tissue microarrays in detecting protein expression and gene amplification in breast cancer

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Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

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Histone deacetylases in replicative senescence: evidence for a senescence-specific form of HDAC-2

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Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

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Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

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The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

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Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

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Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells

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Inhibitors of histone deacetylase arrest cell cycle and induce apoptosis in cervical carcinoma cells circumventing human papillomavirus oncogene expression

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7 January 2021

P21-dependent g(1)arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228

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7 January 2021

New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

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Paclitaxel increases p21 synthesis and accumulation of its AKT-phosphorylated form in the cytoplasm of cancer cells

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Downregulation of p21(waf/cip-1) mediates apoptosis of human hepatocellular carcinoma cells in response to interferon-gamma.

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7 January 2021

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7 January 2021

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7 January 2021

Procaspase 3/p21 complex formation to resist fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase A

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7 January 2021

P21(WAF1/CIP1) is dispensable for G1 arrest, but indispensable for apoptosis induced by sodium butyrate in MCF-7 breast cancer cells.

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7 January 2021

Suppression of mammary carcinoma growth in vitro and in vivo by inducible expression of the Cdk inhibitor p21.

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Isolation of RNA using guanidinium salts

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401567

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665816%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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