Natural regulatory T cells: number and function are normal in the majority of patients with lupus nephritis (Q81342162)

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8 January 2020

title

Natural regulatory T cells: number and function are normal in the majority of patients with lupus nephritis (English)

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8 January 2020

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5

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8 January 2020

author name string

J Yates

1

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8 January 2020

A Whittington

2

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8 January 2020

P Mitchell

3

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8 January 2020

R I Lechler

4

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8 January 2020

G Lombardi

6

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8 January 2020

publication date

23 May 2008

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Clinical and Experimental Immunology

8 January 2020

published in

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8 January 2020

volume

153

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8 January 2020

issue

1

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8 January 2020

page(s)

44-55

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Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus

8 January 2020

cites work

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12 December 2020

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

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Autoreactivity in human IgG+ memory B cells

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Counter-proliferative effects of nucleosomal antigens in cultures from lupus patients

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CD4+CD25high regulatory cells in human peripheral blood

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B cells and professional APCs recruit regulatory T cells via CCL4

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Naturally processed chromatin peptides reveal a major autoepitope that primes pathogenic T and B cells of lupus.

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T cell autoimmunity to histones and nucleosomes is a latent property of the normal immune system

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Control of regulatory T cell development by the transcription factor Foxp3

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Idiotype‐specific CD4+CD25+ T suppressor cells prevent, by limiting antibody diversity, the occurrence of anti‐dextran antibodies crossreacting with histone H3

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12 December 2020

The role of antibodies and B cells in the pathogenesis of lupus nephritis

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12 December 2020

Pathogenesis of systemic lupus erythematosus

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12 December 2020

Regulation by CD25+ lymphocytes of autoantigen-specific T-cell responses in Goodpasture's (anti-GBM) disease

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Quantification of regulatory T cells in patients with systemic lupus erythematosus

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12 December 2020

Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus.

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12 December 2020

A deficiency of CD4+CD25+ T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

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Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus

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Nucleosomes bind to cell surface proteoglycans

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Major peptide autoepitopes for nucleosome-specific T cells of human lupus

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Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma.

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Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses

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Pathogenic autoantibodies in lupus nephritis

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12 December 2020

Very low-dose tolerance with nucleosomal peptides controls lupus and induces potent regulatory T cell subsets

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12 December 2020

MRL/Mp CD4+,CD25- T cells show reduced sensitivity to suppression by CD4+,CD25+ regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosus

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12 December 2020

Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms.

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12 December 2020

Genetic determination of T cell help in loss of tolerance to nuclear antigens

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12 December 2020

Failure of CD25+ T cells from lupus-prone mice to suppress lupus glomerulonephritis and sialoadenitis

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12 December 2020

Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level

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12 December 2020

Genetics of susceptibility and severity in systemic lupus erythematosus

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12 December 2020

Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells

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12 December 2020

Secretion of IFN-gamma and not IL-2 by anergic human T cells correlates with assembly of an immature immune synapse.

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12 December 2020

Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen

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12 December 2020

Global Natural Regulatory T Cell Depletion in Active Systemic Lupus Erythematosus

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12 December 2020

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

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12 December 2020

Regulation of trafficking receptor expression in human forkhead box P3+ regulatory T cells.

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12 December 2020

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

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12 December 2020

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

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12 December 2020

Human regulatory T cells and their role in autoimmune disease

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12 December 2020

The role of CD4CD25 T cells in autoantibody production in murine lupus.

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12 December 2020

Enrichment of CD4+ CD25high T cell population in patients with systemic lupus erythematosus treated with glucocorticoids

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12 December 2020

Regulatory T cells in patients with systemic lupus erythematosus.

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12 December 2020

Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells

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12 December 2020

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

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12 December 2020

Natural regulatory T cells: mechanisms of suppression

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12 December 2020

Increased expression of the FoxP3 functional marker of regulatory T cells following B cell depletion with rituximab in patients with lupus nephritis.

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12 December 2020

Foxp3 in control of the regulatory T cell lineage

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12 December 2020

Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

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12 December 2020