Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells (Q81357564)

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8 January 2020

title

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells (English)

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8 January 2020

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11

Jay A Berzofsky

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8 January 2020

author name string

Hua Zhang

1

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Kevin S Chua

2

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Martin Guimond

3

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Veena Kapoor

4

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Margaret V Brown

5

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Thomas A Fleisher

6

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Lauren M Long

7

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Donna Bernstein

8

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Brenna J Hill

9

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Daniel C Douek

10

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Charles S Carter

12

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E J Read

13

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Lee J Helman

14

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Crystal L Mackall

15

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publication date

16 October 2005

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8 January 2020

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8 January 2020

volume

11

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8 January 2020

issue

11

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page(s)

1238-1243

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https://scigraph.springernature.com/pub.10.1038/nm1312

8 January 2020

exact match

0 references

cites work

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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7 January 2021

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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7 January 2021

Regulatory T cells in autoimmmunity*.

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7 January 2021

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

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7 January 2021

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

1 reference

7 January 2021

Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period

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7 January 2021

Interleukin 2 signaling is required for CD4(+) regulatory T cell function

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7 January 2021

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

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7 January 2021

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

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7 January 2021

Tolerance, not immunity, crucially depends on IL-2.

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7 January 2021

Interleukin-2: clinical applications

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7 January 2021

CD25+CD4+ T cells contribute to the control of memory CD8+ T cells

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7 January 2021

CD4+CD25high regulatory cells in human peripheral blood

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7 January 2021

Interleukin-2 accelerates CD4 cell reconstitution in HIV-infected patients with severe immunosuppression despite highly active antiretroviral therapy: the ILSTIM study--ANRS 082.

1 reference

7 January 2021

In vivo expansion of CD4CD45RO-CD25 T cells expressing foxP3 in IL-2-treated HIV-infected patients

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7 January 2021

Age-dependent incidence, time course, and consequences of thymic renewal in adults

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7 January 2021

Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors

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7 January 2021

In vivo instruction of suppressor commitment in naive T cells

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7 January 2021

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

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7 January 2021

TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

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7 January 2021

A potential role for interleukin-7 in T-cell homeostasis

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7 January 2021

An essential role for Scurfin in CD4+CD25+ T regulatory cells

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7 January 2021

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

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7 January 2021

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

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7 January 2021

Cutting edge: self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cells

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7 January 2021

Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy

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7 January 2021

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

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7 January 2021

Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

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7 January 2021

Assessment of thymic output in adults after haematopoietic stem-cell transplantation and prediction of T-cell reconstitution

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7 January 2021

Identifiers

DOI

10.1038/NM1312

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8 January 2020

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