New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition (Q81402332)

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8 January 2020

title

New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition (English)

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8 January 2020

1 reference

1

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8 January 2020

Jean-Jacques Kiladjian

7

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8 January 2020

William Vainchenker

11

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8 January 2020

author name string

C Tonetti

2

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8 January 2020

R Besancenot

3

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8 January 2020

L Roy

4

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8 January 2020

C Marty

5

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8 January 2020

P Mossuz

6

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8 January 2020

G Socié

8

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8 January 2020

D Bordessoule

9

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8 January 2020

M-C Le Bousse-Kerdilès

10

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8 January 2020

S Giraudier

12

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8 January 2020

publication date

5 June 2008

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8 January 2020

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8 January 2020

volume

22

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8 January 2020

issue

8

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8 January 2020

page(s)

1557-1566

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https://scigraph.springernature.com/pub.10.1038/leu.2008.137

8 January 2020

exact match

0 references

cites work

The chronic myeloproliferative disorders: clonality and clinical heterogeneity

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7 January 2021

Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis.

1 reference

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7 January 2021

Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.137

7 January 2021

Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice

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7 January 2021

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.137

7 January 2021

A gain-of-function mutation of JAK2 in myeloproliferative disorders

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.137

7 January 2021

Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.137

7 January 2021

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.137

7 January 2021

MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients

1 reference

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7 January 2021

MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia

1 reference

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7 January 2021

An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor.

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7 January 2021

A novel MPL point mutation resulting in thrombopoietin-independent activation

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7 January 2021

Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin

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7 January 2021

A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors

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7 January 2021

Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

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7 January 2021

The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.137

7 January 2021

Photochemical preparation of a pyridone containing tetracycle: a Jak protein kinase inhibitor

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7 January 2021

Targeted expansion of genetically modified bone marrow cells

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7 January 2021

The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells

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https://api.crossref.org/works/10.1038%2FLEU.2008.137

7 January 2021

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

1 reference

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7 January 2021

Activated Jak2 with the V617F point mutation promotes G1/S phase transition

1 reference

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7 January 2021

Phenotypic variations and new mutations in JAK2 V617F-negative polycythemia vera, erythrocytosis, and idiopathic myelofibrosis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.137

7 January 2021