Combining SDF-1/CXCR4 antagonism and chemotherapy in relapsed acute myeloid leukemia (Q81612671)

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10 January 2020

title

Combining SDF-1/CXCR4 antagonism and chemotherapy in relapsed acute myeloid leukemia (English)

1 reference

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10 January 2020

main subject

acute myeloid leukemia

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1

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10 January 2020

6

G Ehninger

1 reference

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10 January 2020

8

M Bornhäuser

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10 January 2020

author name string

S Brenner

2

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10 January 2020

U Oelschlaegel

3

1 reference

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10 January 2020

A Jacobi

4

1 reference

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10 January 2020

H Knoth

5

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10 January 2020

T Illmer

7

1 reference

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10 January 2020

publication date

10 July 2008

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10 January 2020

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10 January 2020

volume

23

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10 January 2020

issue

2

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10 January 2020

page(s)

393-396

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https://scigraph.springernature.com/pub.10.1038/leu.2008.182

10 January 2020

exact match

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cites work

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Uncertainty in the niches that maintain haematopoietic stem cells

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Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

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CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice

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7 January 2021

Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5).

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7 January 2021

Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells.

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7 January 2021

Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia

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7 January 2021

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

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Kinetics of CXCR-4 and adhesion molecule expression during autologous stem cell mobilisation with G-CSF plus AMD3100 in patients with multiple myeloma

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7 January 2021

Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias.

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7 January 2021

Effects of AMD3100 on transmigration and survival of acute myelogenous leukemia cells

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Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro

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Internal tandem duplication of Flt3 modulates chemotaxis and survival of hematopoietic cells by SDF1alpha but negatively regulates marrow homing in vivo

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7 January 2021

Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia

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